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首页> 外文会议>Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE >BION/sup TM/. Bionic neurons for functional and therapeutic electrical stimulation
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BION/sup TM/. Bionic neurons for functional and therapeutic electrical stimulation

机译：BION / sup TM /。仿生神经元用于功能性和治疗性电刺激

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The goal of this project is to develop complete clinical systems for the application of functional electrical stimulation to alleviate disabilities and morbidity associated with musculoskeletal paralysis and atrophy. Over the past 8 years, the authors have designed, built and successfully tested in animals the first device in a new class of implantable electronic interfaces with nerve and muscle. BIONs are hermetically encapsulated, leadless electrical devices that are small enough to be injected percutaneously into muscles (2 mm diameter by 15 mm long). They receive their power and digital addressing and command signals from an external transmitter coil that can be worn by or placed under the patient. The authors have designed and built a family of accessory items required for clinical trials, including sterile testing and insertion tools and a bedside control unit so that clinicians can program various patterns of therapeutic stimulation to build strength and bulk in hypotrophic muscles, e.g. following stroke, spinal cord injury, major trauma and orthopedic reconstructions. Other potential applications include urinary incontinence, prevention of deep vein thrombosis and alleviation of chronic pain. Functional recovery of limb movement requires feedback signals about ongoing movement, for which the authors are developing second-generation BIONs that provide outgoing telemetry of such data.
机译：该项目的目标是开发完整的临床系统，用于应用功能电刺激，以缓解与肌肉骨骼瘫痪和萎缩相关的残疾和发病率。在过去的8年里，作者在动物中设计，建造和成功测试了一系列具有神经和肌肉的新类植入电子界面中的第一装置。孔是气密包封的，无侵扰的电气装置足够小，以经皮到肌肉（直径为15mm长）的肌肉（2mm直径）。它们从外部发射器线圈接收它们的电力和数字寻址和指令信号，该信号可以佩戴或放置在患者下方。作者设计并制造了临床试验所需的辅助物品系列，包括无菌测试和插入工具以及床头柜控制单元，使得临床医生可以在脐带肌肉中进行各种治疗刺激模式，以在腹卵磷酸肌肉中构建强度和散装。卒中后，脊髓损伤，主要创伤和整形外科重建。其他潜在应用包括尿失禁，预防深静脉血栓形成和减轻慢性疼痛。肢体运动的功能恢复需要关于正在进行的运动的反馈信号，作者正在开发那些提供这种数据的传出遥测的第二代晶片。

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