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Nanoparticles as contrasting agents in diffuse optical spectroscopy

机译：纳米粒子作为漫反射光谱中的对比剂

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We report the results of study of gold and silicon nanoparticles as contrasting agents for diffuse optical spectroscopy (DOS). Optical properties of the nanoparticles suspensions and model objects were obtained from spectrophotometric measurements in the wavelength range of 500-1100 nm. The DOS measurements were performed with a liquid phantom consisting of water, lipofundin and ink mixture providing optical properties of the solution close to those of biotissue. The phantom contained an inclusion filled with lipofundin and aqueous suspension of gold nanoparticles (GNPs) which were characterized by strong absorption in the red and near infrared spectral range. The inclusion contrast in the obtained DOS images was estimated, which allowed to consider the selected GNPs as potentially perspective contrast agents for DOS applications.
机译：我们报告了金和硅纳米颗粒的研究结果作为弥漫光谱（DOS）的对比剂。纳米颗粒悬浮液和模型对象的光学性质在500-1100nm的波长范围内的分光光度测量获得。用由水，脂质蛋白和油墨混合物组成的液体幻影进行DOS测量，提供靠近生物筛作的溶液的光学性质。幻像含有填充有脂质蛋白的包含金纳米蛋白（GNP）的含水悬浮液，其特征在于红色和近红外光谱范围内的强吸收。估计所获得的DOS图像中的包含对比度，其允许将所选GNP视为DOS应用的可能透视造影剂。

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