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首页> 外文会议>The 3rd Workshop on Scientific Approaches to Chinese Medicine(第三届中医科学研究方法研讨会)论文集 >Effects of 650 nm-10.6 μm Combined Laser Acupuncture-Moxibustion on Knee Osteoarthritis:A Randomized,Double-blinded and Placebo-controlled Clinical Trial
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Effects of 650 nm-10.6 μm Combined Laser Acupuncture-Moxibustion on Knee Osteoarthritis:A Randomized,Double-blinded and Placebo-controlled Clinical Trial

机译：650 nm-10.6μm联合激光针灸对膝骨关节炎的影响：一项随机，双盲和安慰剂对照的临床试验

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Objective: To evaluate the effects of 650 nm-10.6 μm combined laser in patients with knee Osteoarthritis (OA) and to determine whether the combined laser provides greater pain relief and improved function compared with red light.Methods: Forty-eight patients with knee OA were randomly allocated to two groups (24 per group),receiving 20 min irradiation with 650 nm -10.6 μm combined laser or red light emitting diode respectively on point Dubi (ST 35) 3 times a week for the first course (2 weeks) and twice a week for the second one (4 weeks).The main outcome measures were WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores.In addition,patients' global assessment,adverse effects and validation of patient blinding were analyzed.Results:All the patients completed the first course,but 12 were lost during the second one.Due to the high dropout rate by the second course,only the data acquired from the first course could be analyzed.No differences of general data of patients and WOMAC scores were found in between-group comparison before treatment (P>0.05).The WOMAC scores of patients in both combined laser group and red light groupreduced significantly compared to baseline by the end of the first course (P<0.01).There were no significant differences on the reduction rate of WOMAC scores between two groups (P>0.05).Neither the patients' global assessment nor the dropout rate showed statistical differences between two groups (P>0.05).There was no difference between two groups in patients correctly guessing the treatment assignment (P>0.05).There was no significant difference in the reduction rate of WOMAC scores and the patients'global assessment between patients who guessed their assignment (P>0.05).Conclusion:Both combined laser and red light irradiation are beneficial to patients with knee OA.But as the statistical indifferences between two groups,the authors can't conclude from this study whether the combined laser is more effective.
机译：目的：评估650 nm-10.6μm联合激光对膝骨关节炎（OA）患者的疗效，并确定与红光相比，联合激光是否可提供更大的疼痛缓解和改善的功能。方法：48例膝OA患者随机分为两组（每组24个），第一个疗程（2周）每周3次，分别在Dubi点（ST 35）上接受650 nm -10.6μm组合激光或红色发光二极管照射20分钟，第二周（4周）每周两次。主要结局指标为WOMAC（西安大略和麦克马斯特大学骨关节炎指数）评分。此外，还分析了患者的整体评估，不良反应和患者盲法验证。结果：全部患者完成了第一疗程，但是在第二疗程中丢失了12位。由于第二疗程的辍学率很高，因此只能分析从第一疗程获得的数据。在治疗前的组间比较中发现WOMAC评分和WOMAC评分（P> 0.05）。激光组和红光组患者的WOMAC评分在第一疗程结束时均较基线显着降低（P <0.01）。两组之间WOMAC评分降低率无显着差异（P> 0.05），两组患者总体评估和辍学率均无统计学差异（P> 0.05），两组无差异。正确猜出治疗方案的患者中（P> 0.05）。WOMAC得分的降低率与猜出其方案的患者之间的总体评估无显着差异（P> 0.05）。结论：激光和红色相结合光照射对膝骨关节炎患者是有益的。但是由于两组之间的统计差异，作者无法从这项研究中得出联合激光是否更有效的结论。

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