首页> 外文会议>Computers in Cardiology, 2009 >Influence of ischemia and reperfusion duration on left ventricular depolarization in isolated rabbit hearts registered by optical method
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Influence of ischemia and reperfusion duration on left ventricular depolarization in isolated rabbit hearts registered by optical method

机译:缺血再灌注时间对光学法记录离体兔心脏左室去极化的影响

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The influence of ischemia and reperfusion duration on left ventricular depolarization is studied from electrograms (ECG) and monophasic action potentials (MAPs) recorded by optical method. Left ventricular depolarization is evaluated by activation time (AT), which is defined as the distance from the earliest QRS deflection to the MAP upstroke and which describes time duration of depolarization propagation. The excitement conduction in ischemic heart takes longer time in comparison to non-ischemic myocardium. Speed of impulse conduction decreases with ongoing ischemia, and thus the activation time increases proportionally to ischemia duration. During reperfusion, speed of impulse conduction increases immediately with the first minute of reperfusion and remains at the same value till the end of examined period.
机译:通过光学方法记录的电描记图(ECG)和单相动作电位(MAPs),研究了缺血和再灌注持续时间对左心室去极化的影响。左心室去极化通过激活时间(AT)进行评估,激活时间定义为从最早QRS偏转到MAP上冲程的距离,并描述去极化传播的持续时间。与非缺血性心肌相比,缺血性心脏的兴奋传导需要更长的时间。脉冲传导的速度随着正在进行的局部缺血而降低,因此激活时间与局部缺血持续时间成比例地增加。在再灌注过程中,脉冲传导的速度随再灌注的第一分钟立即增加,并保持相同的值,直到检查期结束。

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