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首页> 外文会议>ASME summer bioengineering conference;SBC2009 >BIOMECHANICS OF THE POSTERIOR POLE DURING THE REMODELING PROGRESSION FROM NORMAL TO EARLY EXPERIMENTAL GLAUCOMA
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BIOMECHANICS OF THE POSTERIOR POLE DURING THE REMODELING PROGRESSION FROM NORMAL TO EARLY EXPERIMENTAL GLAUCOMA

机译：从正常到早期实验性青光眼重塑过程中后极的生物力学

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摘要

None of the changes in tissue anatomy and mechanical properties that occur in the progression from normal to early experimental glaucoma led to increases in stress, while many led to decreases. The results were less straightforward for LC strain and displacement, where some factors changed the response one way and others the other way. Although most of the biological processes involved are still unknown, these results suggest that elevated IOP may trigger remodeling of the ocular tissues that act to reduce IOP-induced stresses and anterior-posterior displacements. The reductions are achieved by a nonlinear combination of changes in the shape and stiffness of the tissues of the ONH.
机译：从正常青光眼到早期实验性青光眼的进展中发生的组织解剖学和机械特性变化均未导致压力增加，而许多却导致压力降低。对于LC应变和位移，结果并非那么直接，其中某些因素以一种方式改变了响应，而另一些因素则以另一种方式改变了响应。尽管所涉及的大多数生物学过程仍是未知的，但这些结果表明，眼压升高可能会触发眼组织重塑，从而减轻眼压引起的压力和前后移位。减少是通过ONH组织的形状和硬度变化的非线性组合来实现的。

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