FINITE ELEMENT MODELING OF ENTANGLED COLLAGEN FIBER GELS WITH RANDOMLY ORIENTED FIBERS

机译：带有随机取向纤维的纠缠胶原纤维的有限元建模

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Collagen is an important structural protein in the human body, and its molecules form structural aggregates at multiple length scales (i.e., microfibrils, fibrils, fibers, and bundles of different sizes) in biological tissues and organs [1]. The mechanical properties of most tissues are dependent on the underlying network of collagen fibers, proteoglycans, and other extracellular matrix components [2]. Similarly, the properties of in vitro tissue analogs, often created from collagen or fibrin gels, are also dependent on the organization of the biopolymers [3]. The overall mechanical response is intrinsically multi-scale and dynamic in both materials. As a result, a satisfactory description of the microstructure is important for exploring the essential physics of the tissue.

机译：胶原蛋白是人体中重要的结构蛋白，其分子在生物组织和器官中以多种长度尺度（即微纤维，原纤维，纤维和不同大小的束）形成结构聚集体[1]。大多数组织的机械性能取决于胶原纤维，蛋白聚糖和其他细胞外基质成分的基本网络[2]。同样，通常由胶原蛋白或纤维蛋白凝胶产生的体外组织类似物的特性也取决于生物聚合物的组织[3]。两种材料的整体机械响应本质上都是多尺度的，并且是动态的。结果，对微结构的令人满意的描述对于探索组织的基本物理学是重要的。

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《ASME summer bioengineering conference;SBC2009》|2009年|P.1041-1042|共2页
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Xiaoyue Ma; J. Edward F. Green; Keith J. Gooch; Rebecca M. Jansen; Richard T. Hart;
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中图分类人体工程学;
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2. Misplaced Golgi Elements Produce Randomly Oriented Microtubules and Aberrant Cortical Arrays of Microtubules in Dystrophic Skeletal Muscle Fibers [J] . Sarah Oddoux, Davide Randazzo, Aster Kenea, Frontiers in Cell and Developmental Biology . 2019,第1期

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3. Modeling Random Short Nanofiber- and Microfiber-Reinforced Composites Using the Extended Finite-Element Method [J] . Matthew G. Pike, Caglar Oskay Journal of Nanomechanics and Micromechanics . 2015,第1期

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4. Investigation of the role of crimps in collagen fibers in tendon with a microstructually based finite element model [C] . Vickie Shim, Justin Fernandez, Thor Besier, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2012

机译：用微晶基于细胞有限元模型对肌腱纤维胶凝纤维在胶带中的作用研究
5. Finite element modeling of collagen fibers in the mechanical interaction between cells and the extracellular matrix [D] . Ma, Xiaoyue 2012

机译：细胞与细胞外基质之间机械相互作用中胶原纤维的有限元建模
6. Misplaced Golgi Elements Produce Randomly Oriented Microtubules and Aberrant Cortical Arrays of Microtubules in Dystrophic Skeletal Muscle Fibers [O] . Sarah Oddoux, Davide Randazzo, Aster Kenea, 2019

机译：放错位置的高尔基体元素在营养不良的骨骼肌纤维中产生随机定向的微管和微管的异常皮质阵列。
7. Young’s Modulus estimation techniques for the randomly oriented natural fiber reinforced composites: Finite Element Analysis and Analytical Models [O] . Mehmet Safa Bodur, Mustafa Bakkal 2019

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8. Finite element modeling of evaporation and condensation during sol-gel film and fiber formation. [R] . Schunk, P. R., Hurd, A. J., Brinker, C. J., 1993

机译：溶胶 - 凝胶薄膜和纤维形成过程中蒸发和冷凝的有限元模拟。

FINITE ELEMENT MODELING OF ENTANGLED COLLAGEN FIBER GELS WITH RANDOMLY ORIENTED FIBERS

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