AN ANALYTICAL MODEL OF THE INSTANTANEOUS TRANSVALVULAR PRESSURE GRADIENT THROUGH AN AORTIC STENOSIS

机译：主动脉狭窄的瞬时经瓣压梯度的解析模型

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Diagnosis and treatment of aortic stenosis largely depends on accurate determination of the pressure difference before and after the valve, known as transvalvular pressure gradient (TPG). Clinically, TPG is obtained using Doppler echocardiography though sometimes invasive cardiac catheterization has to be used to confirm Doppler echocardiography findings. By solving analytically coupled fluid and solid domain equations, we suggest a formulation that with a good degree of accuracy can be used to calculate TPG . Analytical result is validated using experimental data from literature. The suggested methodology is an alternative to cardiac catheterization and helps to prevent its risks.

机译：主动脉瓣狭窄的诊断和治疗很大程度上取决于准确确定瓣膜前后的压力差，即跨瓣压力梯度（TPG）。在临床上，TPG是使用多普勒超声心动图获得的，尽管有时必须使用侵入性心脏导管检查来确认多普勒超声心动图的发现。通过求解流体和固相域方程的解析耦合，我们提出了一种公式，该公式可以以较高的精确度来计算TPG。使用来自文献的实验数据验证分析结果。建议的方法是心脏导管插入术的替代方法，有助于预防其风险。

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《ASME Joint US-European Fluids Engineering Division summer meeting;FEDSM2010》|2011年|p.1885-1888|共4页
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Zahra Keshavarz-Motamed; Nima Maftoon; Lyes Kadem;
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中图分类工程流体力学;
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1. Analytical modeling of the instantaneous maximal transvalvular pressure gradient in aortic stenosis. [J] . Garcia D, Kadem L, Savery D, Journal of Biomechanics . 2006,第16期

机译：主动脉瓣狭窄瞬间最大经瓣压力梯度的分析模型。
2. Modeling of the Instantaneous Transvalvular Pressure Gradient in Aortic Stenosis [J] . Hatoum Hoda, Mo Xiaokui-Molly, Crestanello Juan A., Annals of Biomedical Engineering: The Journal of the Biomedical Engineering Society . 2019,第8期

机译：主动脉狭窄中瞬时翻突压力梯度的建模
3. Impact of concomitant mitral regurgitation on transvalvular gradient and flow in severe aortic stenosis: a systematic ex vivo analysis of a subentity of low-flow low-gradient aortic stenosis [J] . Katte Felix, Franz Marcus, Jung Christian, EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology . 2018,第14期

机译：伴随二尖瓣反流对严重主动脉狭窄的分瓣梯度和流动的影响：一种系统的低流量低梯度主动脉狭窄的下度
4. Explicit analytical models for the aortic transvalvular pressure gradients [C] . Damien Garcia, Lyes Kadem, David Savery, Canadian Congress of Applied Mechanics . 2005

机译：主动脉分布压力梯度的显式分析模型
5. Assessment of the fluid mechanics of aortic valve stenosis with in vitro modeling and control volume analysis. [D] . Heinrich, Russell Shawn. 1997

机译：通过体外建模和控制量分析评估主动脉瓣狭窄的流体力学。
6. Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis [O] . Tim Salinger, Kai Hu, Dan Liu, 2018

机译：中度和重度主动脉瓣狭窄患者合并症与经瓣压梯度进展的关系
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8. Interior Ballistics Modeling: Extensions to the One-Dimensional XKTC code and Analytical Studies of Pressure Gradient for Lumped Parameter Codes [R] . Gough, P. S. 2001

机译：内部弹道建模：一维XKTC代码的扩展和集总参数代码的压力梯度分析研究

AN ANALYTICAL MODEL OF THE INSTANTANEOUS TRANSVALVULAR PRESSURE GRADIENT THROUGH AN AORTIC STENOSIS

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