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首页> 外文会议>IT in Medicine and Education (ITME), 2011 International Symposium on >The dosimetry effect of setup errors for patients with esophageal carcinoma in IG-IMRT
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The dosimetry effect of setup errors for patients with esophageal carcinoma in IG-IMRT

机译：IG-IMRT中食管癌患者设置错误的剂量学效应

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The study aims to measure the setup errors of patients with esophageal carcinoma during the treatment of three dimensional conformal radiotherapy (3DCRT). Through the simulation of the three dimensional treatment planning, evaluate the dosimetry effect of setup errors to GTV, CTV and normal tissues around in the actual treatment. From January 2007 to January 2008, 42 chosen patients with esophageal cancer were given 3DCRT. By applying the EPID, the setup errors were measured. Each patient would be examined six times during the treatment, with the frequency of once a week. The simulation of the setup errors can be achieved by moving the isocenter and then observe and analyze the dose distribution of GTV, CTV and normal tissues. There are three main results. The first one is that the systematic setup errors of the 42 patients, from leftward to rightward, was −2.31mm, and the random errors was 4.42mm, while form forward to backward, the systematic setup errors was −0.55mm, while the random errors was 4.35mm, and form upward to downward, the data were −0.16mm and 4.48mm, respectively. The second one is that the setup errors resulted in dose reduction of GTVD95 with 32cGy and CTVD95 with 88cGy. The last one is that the V20 of lung for PLAN1 and PLAN2 were 22.49±5.20% and 22.02±5.47% respectively. The average doses of heart for PLAN1 and PLAN2 were 2077.62±1292.75cGy and 2036.23±1295.86cGy. In the original plan, no patients whose maximum dose of spinal cord exceeded 4500cGy, while 18 cases (42.86%) in PLAN2 were more than 4500cGy, the maximum dose was 5503.90cGy. In the end, the conclusion is the setup errors lowered the level of dose distribution in the original plan so as to reduce the dose of GTV and CTV, while the doses of lung and heart did not change obviously, however, some patients whose maximum dose of spinal cord may exceeded 4500cGy.
机译：该研究旨在测量三维保形放射治疗（3DCRT）期间食管癌患者的设置误差。通过对三维治疗计划的模拟，评估实际治疗中设置误差对GTV，CTV和周围正常组织的剂量测定效果。从2007年1月至2008年1月，对42例选定的食道癌患者进行了3DCRT治疗。通过应用EPID，可以测量设置错误。每位患者在治疗期间将接受六次检查，每周一次。可以通过移动等角点，然后观察和分析GTV，CTV和正常组织的剂量分布，来实现安装误差的仿真。有三个主要结果。第一个是42例患者从左到右的系统设置误差为-2.31mm，随机误差为4.42mm，从前向后，系统设置误差为-0.55mm，而随机误差为-0.55mm。误差为4.35mm，从上到下，数据分别为-0.16mm和4.48mm。第二个是设置错误导致使用32cGy的GTVD95和使用88cGy的CTVD95的剂量减少。最后一个是PLAN1和PLAN2的肺V20分别为22.49±5.20％和22.02±5.47％。 PLAN1和PLAN2的平均心脏剂量为2077.62±1292.75cGy和2036.23±1295.86cGy。在原始计划中，没有脊髓最大剂量超过4500cGy的患者，而PLAN2中有18例（42.86％）超过4500cGy，最大剂量为5503.90cGy。最后，结论是设置错误降低了原计划中的剂量分布水平，从而降低了GTV和CTV的剂量，而肺和心脏的剂量却没有明显变化，但是，有些患者的最大剂量脊髓可能超过4500cGy。

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