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The medication regularity of traditional Chinese medicine against gout

机译：中药对痛风的用药规律

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Objective: To analyze the component law of Chinese medicines for gout by mutual information mining. Methods: Chinese medicine prescriptions for gout were collected and recorded in the database, and then the frequency analysis of herbs, correlation coefficient between herbs, core combinations of herbs were analyzed by using modified mutual information, complex system entropy cluster and unsupervised hierarchical clustering, respectively. Results: Based on the analysis of 127 Chinese medicine prescriptions for gout, 44 drugs with high-frequency occurrence in these prescriptions, the distribution of nature, flavor and channel entry, 38 high frequency drug combinations, 10 drug combinations with higher confidence coefficient, 16 frequently-used herb pairs and 14 core combinations were founded. Conclusion: Chinese medicines for gout were mainly consist of Chinese medicines used for treating gout were main mainly consist of heat-clearing medicinal, blood-activating medicinal, dampness-draining diuretic medicinal, dampness-resolving medicinal. The treatment principle were main mainly consist of clear heat and dry dampness, induce diuresis to drain dampness, induce diuresis to alleviate edema, activate blood and resolve stasis. The treatment principle for gout is to eliminate the pathogenic factors. Radix Clematidis, Rhizoma Dioscoreae Septemlobae, Cortex Phellodendri, Semen Coicis, Poria, Radix Achyranthis Bidentatae, Rhizoma Atractylodis, Rhizoma Alismatis, Radix Glycyrrhizae and Rhizoma Anemarrhenae are the main herbal drugs used in the treatment of gout.
机译：目的：通过互信息挖掘分析痛风中药的成分规律。方法：收集痛风中药处方并将其记录在数据库中，然后使用改进的互信息法，复杂系统熵聚类和无监督层次聚类分析中草药的频率分析，中草药之间的相关系数，中草药的核心组合。 。结果：在分析痛风中药处方127种，这些处方中频频出现的44种药物，性质，风味和通道进入的分布，38种高频药物组合，10种置信度较高的药物组合，16种基础上，建立了常用草药对和14种核心组合。结论：痛风中药主要是治疗痛风的中药，主要是清热药，活血药，利尿利湿药，化湿利湿药。治疗原则主要是清湿燥湿，利尿排湿，利尿减轻水肿，活血化瘀。痛风的治疗原则是消除致病因素。桔梗，山药根，黄柏，精子，Por，白术，甘草和知母是治疗痛风的主要草药。

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