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首页> 外文会议>ASME bioengineering conference >DESIGNING FOR CROSSLINKED UHMWPE IMPLANTS: CLINICAL CONSEQUENCES OF STRESS CONCENTRATIONS
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DESIGNING FOR CROSSLINKED UHMWPE IMPLANTS: CLINICAL CONSEQUENCES OF STRESS CONCENTRATIONS

机译：交联超高分子量聚乙烯植入物的设计：应力集中的临床后果

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Ultrahigh molecular weight polyethylene (UHMWPE) remains the polymer bearing of choice for total joint replacements (TJR), However, the long-term performance of this polymer has been limited by in vivo wear: UHMWPE wear debris generated in the joint space can travel into the periprosthetic bone, initiating osteolysis and implant loosening. Crosslinked UHMWPE (through ionizing radiation) has demonstrated increased wear resistance, but at the cost of reduced fatigue crack propagation and fracture resistance. Additionally, radiation processes can release free radicals which, when not eliminated through thermal treatment, can increase UHMWPE susceptibility to oxidation and mechanical embrittlement. Such tradeoffs present clinical concerns when implant designs incorporate stress concentrations that experience elevated stresses under loading. These compromises are evaluated through the failure analysis of several crosslinked UHMWPE retrievals that fractured in vivo.
机译：超高分子量聚乙烯（UHMWPE）仍然是用于全关节置换（TJR）的首选聚合物，但是，这种聚合物的长期性能受到体内磨损的限制：关节间隙中产生的UHMWPE磨损碎片会进入假体周围的骨头，开始溶骨和植入物松动。交联的UHMWPE（通过电离辐射）已显示出更高的耐磨性，但以降低疲劳裂纹扩展和抗断裂性为代价。另外，辐射过程会释放出自由基，当不通过热处理消除自由基时，会增加UHMWPE对氧化和机械脆化的敏感性。当植入物设计并入在负荷下承受较高应力的应力集中时，这种折衷会引起临床关注。通过对几种在体内破裂的交联的UHMWPE取材进行失败分析，可以评估这些折衷方案。

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