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Circulating tumor cells

机译:循环肿瘤细胞

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Circulating tumor cells (CTCs) are tumor cells that shed from primary tumor and circulate in peripheral blood, and can be a useful clinical marker in early diagnosis and monitoring therapeutic effects for patients with malignant tumors. Detection of rare CTCs contaminated among a large number of hematologic cells presents a technical challenge, but recent technological advances in detection methods of CTCs, especially development of an automated detection system (the CellSeach system), have made it possible to isolate and quantitatively evaluate CTCs. Here, we reviewed clinical implications of CTCs in thoracic malignant tumors such as primary lung cancer and malignant pleural mesothelioma (MPM).
机译:循环肿瘤细胞(CTC)是从原发性肿瘤脱落并在外周血中循环的肿瘤细胞,可以作为早期诊断和监测恶性肿瘤患者治疗效果的有用临床标志物。检测大量血液细胞中受污染的稀有CTC提出了一项技术挑战,但是CTC检测方法的最新技术进步,特别是自动检测系统(CellSeach系统)的开发使分离和定量评估CTC成为可能。 。在这里,我们审查了原发性肺癌和恶性胸膜间皮瘤(MPM)等胸腔恶性肿瘤中CTC的临床意义。

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