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首页> 外文会议>Sensors, actuators, and microsystems general session;Meeting of The Electrochemical Society >Quantum Dot Based Sensing Platform for Selective Detection of Volatile Organic Compounds and Biomarkers
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Quantum Dot Based Sensing Platform for Selective Detection of Volatile Organic Compounds and Biomarkers

机译：基于量子点的传感平台，用于选择性检测挥发性有机化合物和生物标志物

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摘要

Diagnosing and monitoring diseases such as lung cancer often involves expensive testing in advanced stages of development. An inexpensive method is desired for earlier detection and improved prognosis. Such diseases cause changes in body chemistry that result in the release of volatile organic biomarkers (VOBs) that are often different than those of healthy patients. Therefore, appropriate analysis of patients' breath can lead to early diagnosis and monitoring. The objective of this research is to understand and improve new non-invasive selective sensors to quantify specific VOBs. These sensors consist of mixture of quantum dots and dye. The dye becomes colored when exposed to volatile organic biomarkers without a significant difference in color for different biomarkers. However, when the dye is tethered to quantum dots and exposed to light, the color for each biomarker is quantifiably different. Such a combination creates a sensitive and selective sensor for disease specific VOBs.
机译：诊断和监测疾病（例如肺癌）通常需要在开发的晚期阶段进行昂贵的测试。需要一种便宜的方法来进行早期检测和改善预后。此类疾病会导致人体化学变化，从而导致挥发性有机生物标志物（VOB）的释放，而挥发性有机物生物标志物的释放通常不同于健康患者。因此，对患者呼吸的适当分析可以导致早期诊断和监测。这项研究的目的是了解和改进新型的非侵入式选择性传感器，以量化特定的VOB。这些传感器由量子点和染料的混合物组成。当暴露于挥发性有机生物标记物时，该染料会变色，而对于不同的生物标记物，其颜色没有显着差异。但是，当染料束缚在量子点上并暴露在光线下时，每种生物标记的颜色在数量上是不同的。这样的组合产生了针对疾病特定VOB的灵敏且选择性的传感器。

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