Engineering the next generation of optogenetic reporters to illuminate neuronal activity

机译：设计下一代光遗传学报道分子以阐明神经元活性

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The Campbell group uses protein engineering to develop fluorescent protein-based reporters for cell imaging. I will describe our most recent efforts to engineer an improved generation of reporters for calcium ion, membrane potential, and neurotransmitters.

机译：坎贝尔小组使用蛋白质工程技术来开发基于荧光蛋白质的报告基因，用于细胞成像。我将描述我们最近的工作，以设计出新一代的钙离子，膜电位和神经递质报告基因。

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《Conference on Lasers and Electro-Optics》|2015年|1-1|共1页
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Campbell Robert E.;
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1. Shining a light on optogenetics: Advances in electronics and protein engineering advance the field of optogenetics to study the activity of neuronal networks [J] . Hunter Philip EMBO reports . 2016,第5期

机译：揭示光遗传学：电子学和蛋白质工程学的进步推动了光遗传学领域研究神经元网络的活动
2. Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors, a transgenic Cre-reporter rat, and other neuronal studies [J] . Richie Christopher T., Whitaker Leslie R., Whitaker Keith W., Journal of Neuroscience Methods . 2017,第期

机译：近红外荧光蛋白IRFP713作为用于致硫化素的报告蛋白，转基因CRE-TECHER大鼠和其他神经元研究
3. Sparsened neuronal activity in an optogenetically activated olfactory glomerulus [J] . Oliver Braubach, Tuce Tombaz, Tristan Geiller, Scientific reports. . 2018,第1期

机译：在对近视性嗅觉肾小球中缩小神经元活性
4. Engineering the next generation of optogenetic reporters to illuminate neuronal activity [C] . Campbell Robert E. Conference on Lasers and Electro-Optics . 2015

机译：工程下一代视神经记者来照亮神经元活动
5. Engineering GCaMP affinity and kinetics for improved tracking of neuronal activity. [D] . Sun, Xiaonan Richard. 2012

机译：工程GCaMP亲和力和动力学，可改善对神经元活动的跟踪。
6. Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors a transgenic Cre-reporter rat and other neuronal studies [O] . Christopher T. Richie, Leslie R. Whitaker, Keith W. Whitaker, -1

机译：近红外荧光蛋白iRFP713作为报告蛋白用于光遗传学载体转基因Cre-reporter大鼠和其他神经元研究
7. Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors, a transgenic Cre-reporter rat, and other neuronal studies [O] . Christopher T. Richie, Leslie R. Whitaker, Keith W. Whitaker, 2017

机译：近红外荧光蛋白IRFP713作为用于致敏载体的报告蛋白，转基因Cre-Checioner大鼠和其他神经元研究

Engineering the next generation of optogenetic reporters to illuminate neuronal activity

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