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Electrospun fibers containing cationic quaternary ammonium derivatives with antibacterial activity: Electrospun quaternized polysulfone fibers with antimicrobial activity

机译:包含具有抗菌活性的阳离子季铵衍生物的电纺纤维:具有抗菌活性的电纺季铵化聚砜纤维

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Solutions processable of cationic ionomers have received widespread attention for their promising roles as exchange membranes, antibacterial coatings, and dialysis membranes. Therefore, the solutions of the polysulfone ionomers, with a tunable density of quaternary ammonium functional groups, were processed by electrospinning to create new fibrous materials that can modulate membrane properties. The relationship between processable solution properties and morphological aspects was assessed. Thus, results have shown that the morphology of fibers formed, with different forms and dimensions, could be attributed to the combined effects of the polymer solutions concentration, thermodynamic quality of the used solvents, and implicitly, the cumulative effects of electrostatic interactions, hydrogen bonding or association phenomena. The antibacterial activity of PSFQ fibers against Gram-negative and Gram-positive bacteria has indicated potential for biomedical use.
机译:阳离子离聚物的可加工溶液因其作为交换膜,抗菌涂层和透析膜的有前途的作用而受到广泛关注。因此,通过电纺丝加工具有可调密度的季铵官能团密度的聚砜离聚物溶液,以产生可调节膜性能的新型纤维材料。评估了可处理溶液特性与形态方面之间的关系。因此,结果表明,所形成的纤维具有不同的形式和尺寸,其形态可归因于聚合物溶液浓度,所用溶剂的热力学质量以及隐含的静电相互作用,氢键的累积效应的综合作用。或联想现象。 PSFQ纤维对革兰氏阴性和革兰氏阳性细菌的抗菌活性表明了其在生物医学领域的潜力。

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