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Quantification of apparent diffusion coefficient and relative cerebral blood volume for analysis concerning gender and age as determinant factors in glioma prospect

机译:定量分析表观扩散系数和相对脑血容量,以分析性别和年龄作为胶质瘤前景的决定因素

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The purpose of this paper is to use data provided by diffusion - weighted magnetic resonance imaging (DWI) and perfusion - weighted magnetic resonance imaging (PWI) in order to establish whether age or gender can be factors involved in developing a brain tumor. Moreover, the study aims to conclude if these factors influence the features of a high grade brain tumor. The methods used in order to achieve those purposes included quantification and post-processing of DWI and PWI, which resulted in acquiring apparent diffusion coefficient (ADC) values and relative cerebral blood volumes (rCBV). Twenty-five patients, with an elevated rCBV and a decreased ADC value (conditions that characterize a high grade malignancy) were selected. our results suggest that, although the number of men developing a brain neoplasia is higher, the disease manifestation is worse in women. Also, age proves to be an important factor as people over 45 years old are more prone to be diagnosed with a high grade glioma.
机译:本文的目的是使用扩散加权磁共振成像(DWI)和灌注加权磁共振成像(PWI)提供的数据,以确定年龄或性别是否可能是发展脑瘤的因素。此外,该研究旨在得出结论,这些因素是否会影响高级脑肿瘤的特征。为了达到这些目的而使用的方法包括对DWI和PWI进行量化和后处理,从而获得了表观扩散系数(ADC)值和相对脑血容量(rCBV)。选择了25例rCBV升高且ADC值降低(恶性程度高的疾病)的患者。我们的研究结果表明,尽管发展为脑瘤的男性人数较多,但女性的疾病表现较差。而且,年龄被证明是一个重要因素,因为45岁以上的人更容易被诊断出患有高级别神经胶质瘤。

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