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首页> 外文会议>Conference on Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics >Cadaveric In-Situ Testing of Optical Coherence Tomography System Based Skull Base Surgery Guidance
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Cadaveric In-Situ Testing of Optical Coherence Tomography System Based Skull Base Surgery Guidance

机译：基于颅底手术指南的光学相干断层扫描系统的尸体原位测试

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Optical Coherence Tomography (OCT) has extensive potential for producing clinical impact in the field of neurological diseases. A neurosurgical OCT hand-held forward viewing probe in Bayonet shape has been developed. In this study, we test the feasibility of integrating this imaging probe with modern navigation technology for guidance and monitoring of skull base surgery. Cadaver heads were used to simulate relevant surgical approaches for treatment of sellar, parasellar and skull base pathology. A high-resolution 3D CT scan was performed on the cadaver head to provide baseline data for navigation. The cadaver head was mounted on existing 3- or 4-point fixation systems. Tracking markers were attached to the OCT probe and the surgeon-probe-OCT interface was calibrated. 2D OCT images were shown in real time together with the optical tracking images to the surgeon during surgery. The intraoperative video and multimodality imaging data set, consisting of real time OCT images, OCT probe location registered to neurosurgical navigation were assessed. The integration of intraoperative OCT imaging with navigation technology provides the surgeon with updated image information, which is important to deal with tissue shifts and deformations during surgery. Preliminary results demonstrate that the clinical neurosurgical navigation system can provide the hand held OCT probe gross anatomical localization. The near-histological imaging resolution of intraoperative OCT can improve the identification of microstructural/morphology differences. The OCT imaging data, combined with the neurosurgical navigation tracking has the potential to improve image interpretation, precision and accuracy of the therapeutic procedure.
机译：光学相干断层扫描（OCT）在神经疾病领域产生临床影响具有广泛的潜力。已经开发出了刺刀形状的神经外科OCT手持式前视探头。在这项研究中，我们测试了将该成像探头与现代导航技术集成在一起以指导和监测颅底手术的可行性。尸体头部用于模拟相关的手术方法，以治疗鞍，蝶鞍旁和颅底病变。对尸体头部进行了高分辨率的3D CT扫描，以提供用于导航的基线数据。尸体头安装在现有的三点或四点固定系统上。将跟踪标记物附着在OCT探针上，并校准外科医生-探针-OCT界面。实时显示2D OCT图像以及在手术过程中向医生显示的光学跟踪图像。评估了术中视频和多模态成像数据集，包括实时OCT图像，注册到神经外科导航的OCT探头位置。术中OCT成像与导航技术的集成为外科医生提供了更新的图像信息，这对于处理手术过程中的组织移位和变形非常重要。初步结果表明，临床神经外科手术导航系统可提供手持式OCT探头的总体解剖定位。术中OCT的近组织学成像分辨率可改善对微结构/形态学差异的识别。 OCT成像数据与神经外科手术导航相结合，具有改善图像解释，治疗过程的准确性和准确性的潜力。

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