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Diagnostic Usefulness of Synthetic MMG (SMMG) with DBT (Digital Breast Tomosynthesis) for Clinical Setting in Breast Cancer Screening

机译:合成MMG(SMMG)与DBT(数字化乳房断层合成)在乳腺癌筛查中的临床诊断价值

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We evaluated the diagnostic performance of a novel image processing technique of synthetic MMG (SMMG) as 2D-like visualization approach with and without DBT slice images (DBT) compared with that of 2D MMG (MMG) alone. With one-view MMG and DBT, the radiation doses, utilizing the ACR phantom 156, were 1.20 mGy and 1.80 mGy. The number of the cases was 108. MMG, SMMG, and DBT slice images were evaluated independently by 4 readers utilizing ROC analysis and diagnostic performance. SMMG plus DBT demonstrated higher area under the curve (AUC) and superior diagnostic accuracy with sensitivity, specificity, and NPV compared with SMMG and MMG alone (p < 0.05). In addition, a 40 % decrease of radiation dose with SMMG plus DBT compared with MMG plus DBT as the current setting will enable us to apply a two-view SMMG plus DBT in breast cancer screening instead of MMG.
机译:我们评估了一种新颖的合成MMG(SMMG)图像处理技术作为具有和不具有DBT切片图像(DBT)的2D可视化方法与单独的2D MMG(MMG)相比的诊断性能。对于单视图MMG和DBT,利用ACR体模156的辐射剂量分别为1.20 mGy和1.80 mGy。病例数量为108。MMG,SMMG和DBT切片图像由4位读者利用ROC分析和诊断性能分别进行了评估。与单独使用SMMG和MMG相比,SMMG加DBT表现出更大的曲线下面积(AUC),并具有更高的诊断准确性,敏感性,特异性和NPV(p <0.05)。此外,与当前的设置相比,SMMG + DBT与MMG + DBT相比放射剂量降低了40%,这使我们能够在乳腺癌筛查中代替MMG应用两视图SMMG + DBT。

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