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Evaluation of hepatocellular carcinoma transarterial chemoembolization using 3D contrast enhanced ultrasound time-intensity curve analysis

机译:使用3D对比增强超声时间强度曲线分析评估肝细胞癌经动脉化疗栓塞

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Transarterial chemoembolization (TACE) is a standard care for patients with Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma (HCC) and may also be used as a bridging therapy in patients who are potential transplant candidates. Incomplete treatment is defined as the persistence of enhancing areas inside the treated lesions seen at the first imaging study after locoregional treatment. Current guidelines recommend follow-up MRI or CT imaging 4-6 weeks after treatment. An earlier indicator of residual disease would enable clinicians to re-treat sooner, potentially improving disease control. In this study, a time-intensity curve of 3D contrast-enhanced ultrasound (CEUS) was assessed as a safe, inexpensive, accurate and earlier alternative technique for the identification of TACE patients requiring retreatment.
机译:Cryonterial Chemobolization(TACE)是巴塞罗那临床肝癌阶段B肝细胞癌(HCC)患者的标准护理,也可用作潜在移植候选者的患者的桥接治疗。不完全治疗被定义为在局部处理后第一次成像研究中看到的治疗病变内的增强区域的持续存在。目前的指南建议治疗后4-6周的后续MRI或CT成像。较早的残留疾病指标将使临床医生能够迅速重新治疗,可能会改善疾病控制。在该研究中,评估了3D对比度增强超声(CEU)的时间强度曲线作为安全,廉价,准确和更早的替代技术,用于鉴定需要撤退的TACE患者。

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