• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>SPIE Medical Imaging Conference >Towards determination of individual glandular dose
【24h】

Towards determination of individual glandular dose

机译：确定单个腺体剂量

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Due to variations in amount and distribution of glandular breast tissue among women, the mean glandular dose (MGD) can be a poor measure of the individual glandular dose. Therefore, to improve the basis for risk assessment related to radiation dose from breast X-ray examinations, the distribution should be considered. Breast tomosynthesis (BT) is an imaging technique that may be used as an alternative or complement to standard mammography in breast cancer screening, and it could provide the required 3D-localisation of glandular tissue for estimation of the individual glandular dose. In this study, we investigated the possibility to localize glandular tissue from BT data and use a Monte Carlo simulation routine to estimate the glandular dose for software breast phantoms with different amount and distribution of glandular breast tissue. As an initial evaluation of the method, the local energy absorption in glandular tissue was estimated for seven breast phantoms and the corresponding phantoms recreated from reconstructed BT data. As expected, the normalized glandular dose was found to differ substantially with glandular distribution. This emphasizes the importance of glandular tissue localization for estimation of the individual glandular dose. The results showed good accuracy for estimation of normalized glandular dose using breast phantoms recreated from reconstructed BT image volumes (relative differences between -7.3% and +9.5%). Following this initial study, the method will be evaluated for more phantoms and potentially developed for patient cases. In the future it could become a useful tool in breast dosimetry as a step towards the individual glandular dose.
机译：由于女性中腺乳腺组织的数量和分布存在差异，因此，平均腺体剂量（MGD）不能很好地衡量各个腺体的剂量。因此，为了改善与乳房X线检查放射剂量有关的风险评估的基础，应考虑分布。乳房断层合成（BT）是一种影像技术，可以用作乳腺癌筛查中标准乳房X线照相术的替代或补充，它可以提供腺体组织所需的3D定位，以估计各个腺体的剂量。在这项研究中，我们调查了从BT数据中定位腺体组织的可能性，并使用Monte Carlo模拟例程来估算具有不同数量和分布腺体乳腺组织的软件乳房模型的腺体剂量。作为对该方法的初步评估，估计了七个乳腺体模在腺体组织中的局部能量吸收，并从重建的BT数据中重新创建了相应的体模。如预期的那样，发现标准化的腺体剂量随腺体分布而显着不同。这强调了腺组织定位对于估计单个腺剂量的重要性。结果表明，使用从重建的BT图像体积重新创建的乳房幻像来估算标准化腺体剂量的准确性很高（相对差异在-7.3％和+ 9.5％之间）。经过最初的研究，将对该方法进行更多的幻影评估，并可能针对患者病例开发该方法。将来，它可能会成为乳房剂量测定中的有用工具，成为朝着单个腺体剂量迈出的一步。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号