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Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections

机译:神经介入预测随成人头部大小和儿童年龄器官剂量变化的研究

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The purpose of this study was to evaluate the effect of patient head size on radiation dose to radiosensitive organs, such as the eye lens, brain and spinal cord in fluoroscopically guided neuro-interventional procedures and CBCT scans of the head. The Toshiba Infinix C-Arm System was modeled in BEAMnrc/EGSnrc Monte-Carlo code and patient organ and effective doses were calculated in DOSxynrc/EGSnrc for CBCT and interventional procedures. X-ray projections from different angles, CBCT scans, and neuro-interventional procedures were simulated on a computational head phantom for the range of head sizes in the adult population and for different pediatric ages. The difference of left-eye lens dose between the mean head size and the mean ± 1 standard deviation (SD) ranges from 20% to 300% for projection angles of 0° to 90° RAO. The differences for other organs do not vary as much and is only about 10% for the brain. For a LCI-High CBCT protocol, the difference between mean and mean ± 1 SD head size is about 100% for lens dose and only 10% for mean and peak brain dose; the difference between 20 and 3 year-old mean head size is an increase of about 200% for the eye lens dose and only 30% for mean and peak brain dose. Dose for all organs increases with decreasing head size for the same reference point air kerma. These results will allow size-specific dose estimates to be made using software such as our dose tracking system (DTS).
机译:这项研究的目的是评估在荧光透视引导的神经介入程序和头部的CBCT扫描中,患者头部大小对辐射敏感器官(例如,晶状体,脑和脊髓)的辐射剂量的影响。东芝Infinix C臂系统以BEAMnrc / EGSnrc蒙特卡罗代码和患者器官为模型,并在DOSxynrc / EGSnrc中为CBCT和介入程序计算有效剂量。在计算的人体模型上模拟了来自不同角度的X射线投影,CBCT扫描和神经干预程序,以了解成年人口和不同儿童年龄的头部大小范围。对于0°至90°RAO的投影角度,平均头大小与平均值±1标准偏差(SD)之间的左眼镜片剂量之差在20%至300%的范围内。其他器官的差异变化不大,大脑的差异仅为10%。对于LCI-High CBCT方案,晶状体剂量的平均值与平均值±1 SD头大小之间的差异约为100%,而平均值与峰值脑部剂量的差异仅为10%; 20岁和3岁的平均头部大小之间的差异是,晶状体剂量增加了约200%,而平均和峰值脑部剂量仅增加了30%。对于相同的参考点空气比释动能,随着头部尺寸的减小,所有器官的剂量都会增加。这些结果将允许使用诸如我们的剂量跟踪系统(DTS)之类的软件来进行尺寸特定的剂量估算。

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