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Designing a system for forward-viewing 3D intravascular ultrasound imaging of blood flow velocity: assessing the effect of the catheter on velocity estimation in stenoses

机译：设计用于对血流速度进行前视3D血管内超声成像的系统：评估导管对狭窄中速度估计的影响

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Wall shear stress (WSS) has been associated with development of high-risk plaque, which increases the likelihood for major adverse cardiac events. Recently, we have used a catheter-based, 3D intravascular forward-viewing ultrasound (FV US) transducer to directly estimate velocity fields in the femoral artery of a pig. Because inserting a catheter will affect the blood flow dynamics in the artery, in this work, the effects of a catheter on flow dynamics are experimentally quantified in both femoral and coronary stenotic vessels in phantoms to determine conditions in which velocity can be accurately estimated. An external linear array transducer was used to estimate velocity in the lumen at 5000 fps via a particle imaging velocimetry approach. The current study indicates that a hollow, catheter-based FV US could be used to quantify the flow dynamics surrounding stenoses with minimal flow disturbance, and thus could potentially assess elevated WSS and risk of plaque rupture.

机译：壁切应力（WSS）与高危斑块的发展有关，这增加了发生重大不良心脏事件的可能性。最近，我们已使用基于导管的3D血管内前视超声（FV US）换能器直接估算猪股动脉的速度场。由于插入导管会影响动脉中的血流动力学，因此在这项工作中，在幻影的股动脉和冠状动脉狭窄血管中，通过实验量化了导管对血流动力学的影响，以确定可以准确估计速度的条件。使用外部线性阵列换能器通过粒子成像测速方法估算5000 fps的腔内速度。当前的研究表明，空心的，基于导管的FV US可用于以最小的流量扰动来量化狭窄周围的血流动力学，从而有可能评估WSS升高和斑块破裂的风险。

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《IEEE International Ultrasonics Symposium》|2020年|1-4|共4页
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Saeyoung Kim; Bowen Jing; Brooks D. Lindsey;
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Intravascular ultrasound; blood flow velocity estimation; particle image velocimetry; forward viewing;

机译：血管内超声;血流速度估计;粒子图像测速;前视;

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专利

1. Experimental evaluation of velocity and power estimation for ultrasound blood flow imaging, by means of a two-dimensional autocorrelation approach [J] . Loupas T., Peterson R.B. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control . 1995,第4期

机译：二维自相关方法对超声血流成像速度和功率估计的实验评估
2. Comparison of cerebral blood flow velocity estimation with cranial ultrasound imaging for early prediction of outcome in preterm infants. [J] . Rennie JM, Coughtrey H, Morley R, Journal of Clinical Ultrasound: JCU . 1995,第1期

机译：比较脑血流速度估计与颅骨超声成像对早产儿结局的早期预测。
3. Comparison of cerebral blood flow velocity estimation with cranial ultrasound imaging for early prediction of outcome in preterm infants. [J] . Rennie JM, Coughtrey H, Morley R, Journal of Clinical Ultrasound: JCU . 1995,第1期

机译：比较脑血流速度估计与颅骨超声成像对早产儿结局的早期预测。
4. System for real-time forward-viewing intravascular imaging of 3D velocity fields [C] . Brooks D. Lindsey, Bowen Jing, Graham Collins, IEEE International Ultrasonics Symposium . 2019

机译：用于实时正向观察3D速度场的血管内成像系统
5. Two-dimensional blood flow velocity estimation using ultrasound speckle pattern dependence on scan direction and velocity. [D] . Xu, Tiantian. 2012

机译：使用超声斑点图案的二维血流速度估计值取决于扫描方向和速度。
6. Evaluation of ultrasound Tissue Velocity Imaging: a phantom study of velocity estimation in skeletal muscle low-level contractions [O] . Frida Lindberg, Mattias Mårtensson, Christer Grönlund, 2013

机译：超声组织速度成像的评估：骨骼肌低水平收缩速度估计的幻像研究
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Designing a system for forward-viewing 3D intravascular ultrasound imaging of blood flow velocity: assessing the effect of the catheter on velocity estimation in stenoses

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