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首页> 外文会议>IEEE International Conference on Electronics, Computing and Communication Technologies >A Pilot Study on Amblyopic Children for Possible Quantification of the Left/Right Mismatch
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A Pilot Study on Amblyopic Children for Possible Quantification of the Left/Right Mismatch

机译：弱视儿童对左/右错配可能量化的初步研究

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Amblyopia is a childhood eye condition with low vision in one or rarely both eyes, due to suppression at the visual cortex, that persists after rectification of risk factor at eye level. For an amblyopic child, the visual inputs from the amblyopic eye (AE) is suppressed at the brain. This leads to reduced visual acuity and poor or complete loss of stereopsis. Conventional clinical tests such as Worth 4-dot test and Bagolini striated lens test can only detect the presence of suppression but cannot quantify the extent of suppression, which is important for quantifying and identifying the effectiveness of treatments for amblyopia. In this paper, we propose a possible cost-effective and child-friendly method for quantifying the level of ocular suppression in amblyopia. The procedure is based on the fact that for amblyopic subjects, there is an asymmetry in the amount of ocular suppression experienced by the AE and this suppression leads to an inferior performance of the AE in an image recognition task. Preliminary studies performed on six each of control and amblyopic subjects are presented in this paper. We have shown that the absolute value of the deviation of the ratio of accuracies of both eyes in an image recognition task from unity can be used as a measure of the suppression. Paired t-test revealed a significant difference between the means of the accuracies of amblyopic and fellow eyes (p=0.03) in the case of amblyopic subjects. Equivalence test done using ‘two-one-sided t-tests’ procedure shows that the equivalence of the accuracies of left and right eyes for control is statistically significant (p = 0.008, symmetric equivalence margin of 5 percentage points).
机译：弱视是一种儿童眼睛疾病，由于对视皮层的抑制作用，一只眼睛或两只眼睛很少视力低下，这种风险在矫正视线水平的危险因素后仍然存在。对于弱视儿童，弱视眼（AE）的视觉输入在大脑中受到抑制。这导致视敏度降低以及立体视差或完全丧失。常规的临床测试，例如沃思4点测试和Bagolini横纹状眼镜测试只能检测抑制的存在，而不能量化抑制的程度，这对于量化和识别弱视治疗的有效性非常重要。在本文中，我们提出了一种可能的经济有效且对儿童友好的方法，用于量化弱视的眼抑制水平。该程序基于以下事实：对于弱视受试者，AE经历的眼抑制量存在不对称性，并且这种抑制导致AE在图像识别任务中的性能较差。本文介绍了对六个对照和弱视受试者进行的初步研究。我们已经表明，可以将图像识别任务中两只眼睛的准确率之比的偏差的绝对值的绝对值用作抑制的量度。配对t检验显示，在弱视受试者的情况下，弱视和同眼的准确性之间存在显着差异（p = 0.03）。使用“双面t检验”程序进行的等效性测试表明，控制用左眼和右眼的等效性具有统计学意义（p = 0.008，对称等效性裕度为5个百分点）。

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