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首页> 外文会议>National Conference on Biomedical Engineering;International Iranian Conference on Biomedical Engineering >Fixel-Based Analysis of White Matter in Temporal Lobe Epilepsy
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Fixel-Based Analysis of White Matter in Temporal Lobe Epilepsy

机译：基于Fixel的颞叶癫痫白质分析

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Temporal lobe epilepsy (TLE) has been investigated by many researchers in the last two decades. Many efforts have been done based on magnetic resonance imaging (MRI) data such as identifying the TLE type, identifying the missing links, and automatically classifying epileptic subjects. Investigating TLE patients has paved the way for introducing, comparing, and developing new algorithms on diffusion weighted imaging (DWI) data. Fixel study is one of the newest methods for DWI analysis. Superiority of this method over other methods such as diffusion tensor imaging (DTI) is in correct recording of cross-over fibers. Furthermore, combination of fiber density and fiber cross-section measures has created a suitable method for group studies. Using fixel-based analysis, we have depicted the most important alterations in the fiber density of TLE patients. Statistically significant alteration in the ipsilateral hemisphere has been demonstrated for both right and left TLE. Superiority of fiber density and cross-section (FDC) over fiber density (FD) for TLE studies is illustrated.
机译：在过去的二十年中，许多研究人员对颞叶癫痫病（TLE）进行了研究。基于磁共振成像（MRI）数据已进行了许多努力，例如识别TLE类型，识别缺失的链接以及自动对癫痫对象进行分类。对TLE患者的研究为弥散加权成像（DWI）数据的引入，比较和开发新算法铺平了道路。 Fixel研究是DWI分析的最新方法之一。该方法相对于其他方法（如扩散张量成像（DTI））的优势在于正确记录了交叉纤维。此外，纤维密度和纤维横截面测量值的组合为分组研究创造了一种合适的方法。使用基于fixel的分析，我们描述了TLE患者纤维密度中最重要的变化。左右TLE均在同侧半球发生了统计学上的显着变化。说明了用于TLE研究的纤维密度和横截面（FDC）优于纤维密度（FD）。

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