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首页> 外文会议>National Conference on Biomedical Engineering;International Iranian Conference on Biomedical Engineering >Studying the Effects of Different Inter-Stimulus-Intervals in ADHD Adults While Performing CPT
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Studying the Effects of Different Inter-Stimulus-Intervals in ADHD Adults While Performing CPT

机译：在进行CPT时研究ADHD成人不同刺激间隔的影响

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Event-related potentials were investigated in this study while participants were performing a continuous performance task (CPT). A 21 electrode EEG signal was recorded in a 10-20 standard system from 50 healthy and ADHD adult subjects. After the basic pre-processing steps (band-pass and notch filtering, re-referencing and baseline rejection) Independent component analysis (ICA) was used to diminish the remaining EOG artifact. Then, event-related potentials were calculated using the time locked epochs of the cleaned signal. Afterwards, P300 morphological features such as peak amplitude and latency, were extracted and then the statistical process was carried out, to determine if the peak amplitudes and latencies have significant difference among healthy and ADHD subjects and in different inter-stimulus-intervals (ISIs). Our results show that as ISI gets longer, the difference in P300 latency between ADHD and healthy subjects gets bolder, statistical analysis and p-value confirm these results. Also, further statistic analysis is performed to figure out the effect of ISI variations in latency and peak amplitude of P300 in every subject; longer ISI leads to an increase in the latency of P300 in ADHD subjects.
机译：在本研究中调查了与事件相关的潜力，而参与者正在执行连续的性能任务（CPT）。在50个健康和ADHD成人受试者的10-20个标准系统中记录了21个电极EEG信号。在基本的预处理步骤（带通和凹口滤波，重新参考和基线抑制）之后，使用独立分量分析（ICA）来缩小剩余的EOG伪影。然后，使用清洁信号的时间锁定时期计算事件相关电位。之后，提取P300的形态特征，例如峰值幅度和潜伏期，然后进行统计过程，以确定峰值幅度和延迟是否具有对健康和ADHD受试者的巨大差异，并且以不同的刺激间隔（ISIS） 。我们的结果表明，随着ISI变长，ADHD和健康受试者之间的P300延迟差异变得更大胆，统计分析和P值确认这些结果。此外，进行了进一步的统计分析，以确定每个主题中P300的潜伏期和峰值幅度的ISI变化的影响;更长的ISI导致ADHD受试者P300潜伏期的增加。

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