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Preliminary results from clinical validation study of a method for non-invasive assessment of atrioventricular node refractoriness during atrial fibrillation

机译:房颤期间房室结难治性的非侵入性评估方法的临床验证研究的初步结果

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The purpose of this study is to evaluate our previously proposed model-based, non-invasive approach to assess atrioventricular (AV) node refractory periods during atrial fibrillation (AF) by comparing its estimates to the invasively assessed AV node refractory periods. Patients referred to the hospital for pulmonary vein isolation (PVI), being in AF upon arrival, are included in the study. Using our approach, we estimate the AV node refractory periods from the ECG before and during the PVI procedure. The refractory periods is estimated using both single and dual pathway models; Bayes Information Criterion is employed to select the most appropriate model. Following conversion to sinus rhythm, a S1S2 atrial pacing protocol is applied to invasively assess AV node refractory periods. Preliminary results suggest that the method for non-invasive assessment of AV node refractoriness is accurate, however, more data is needed to better establish performance.
机译:这项研究的目的是评估我们先前提出的基于模型的非侵入性方法,通过将其估计值与侵入性评估的AV节点不应期相比较来评估房颤(AF)的房室(AV)节点不应期。该研究包括到达医院时因房颤而被转诊到医院进行肺静脉隔离(PVI)的患者。使用我们的方法,我们可以在PVI程序之前和期间通过ECG估算AV节点的不应期。使用单路径和双路径模型估计不应期。使用贝叶斯信息准则来选择最合适的模型。转换为窦性心律后,将S1S2心房起搏协议用于侵入性评估房室结的不应期。初步结果表明,无创评估房室结耐火度的方法是准确的,但是,需要更多的数据来更好地建立性能。

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