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Reliable drug release testing for electrotransport systems

机译:Electransport系统可靠的药物释放测试

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Electrotransport Systems (ETS) for transdermal drug delivery use ionic currents to deliver substances across the skin. ALZA Corporation is developing an ETS for the on-demand deliveyr of fentanyl to treat acute pain. The ETS is self contained, incorporating control electronics, a battery, and two hydrogel/electrode assemblies in a small patch that is applied to the upper arm or chest. The device is worn for 24 hours and provides mutliple doses: for each dose the patient receives a predetermined amount of fentanyl over a brief period by pressing a button. The device is similar to that used in recent clinical studies~1.
机译:用于透皮药物递送的Electransport系统(ETS)使用离子电流来递送皮肤的物质。 Alza Corporation正在为芬太尼的按需Delideyr开发ETS,以治疗急性疼痛。 ETS是自包含的,包括控制电子设备,电池和两个水凝胶/电极组件,在施加到上臂或胸部的小贴片中。该器件佩戴24小时,并提供Mutliple剂量:对于每种剂量,患者通过按下按钮在短时间内接收预定量的芬太尼。该装置类似于最近临床研究中使用的那样〜1。

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