Heart state information and neural control expounded by parameters are useful to early diagnose heart diseases. The purpose of this article was to investigate the efficiency of parameters that express heart state variation and neural control. We have studied three kinds of parameters: global, local and dynamic ones with different method confirmation to extract heart concealed physiological and pathological information with animal models. Pathological notch on QRS complex of electrocardiogram (ECG) is defined as local parameter which is one of high-frequency components (HFCs) and poincare dispersed-dot plot (PDDP) is defined as nonlinear global one. Pathological notching information on the QRS complex is related with myocardial injuries. A large number of repetitive experiments indicated that both parameters showed that they have sensitive and early response of heart state pathological variation and also have dynamic characteristics.
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