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APPLICATION OF A NOVEL PRE-CHARGED AND HIGHLY SPECIFIC FLUORINATED AZIDE FOR THE TRACE ANALYSIS OF ETHINYL ESTRADIOL USING A COPPERCATALYZED CLICK REACTION

机译：使用铜催化鼠标咔哒咔哒咔哒咔哒咔哒咔啉代用预充电和高度氟化叠氮化物用于乙炔雌二醇的痕量分析

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A novel pre-charged and highly specific fluorinated azide (17F-N3) derivatization agent was conveniently synthesized in good yield and characterized using MS and NMR. The 17F-N3 reacted with alkyne-bearing ethinyl estradiol (EE2) by coppercatalyzed click reaction and the time course mass spectral analysis showed the completion of reaction after 45 minutes of incubation.

机译：一种新的预充电和高度特异性的氟化叠氮化物（17F-N3）衍生化剂以良好的产量方便地合成，并使用MS和NMR表征。通过铜催化的咔哒反应与炔烃乙炔雌二醇（EE2）反应的17F-N3反应，时间课程质谱分析显示在45分钟孵育后的反应完成。

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《ASMS Conference on Mass Spectrometry and Allied Topics》|2014年||共1页
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Priyanka Chitranshi; Lucie Loukotkova; Goncalo Gamboa da Costa;
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中图分类 TB994.5-53;
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1. Original fluorinated copolymers achieved by both azide/alkyne 'Click' reaction and hay coupling from tetrafluoroethylene telomers [J] . Soules A., Ameduri B., Boutevin B., Macromolecules . 2010,第10期

机译：通过叠氮化物/炔烃的“点击”反应和四氟乙烯调聚物的干草耦合获得的原始氟化共聚物
2. A selective and highly sensitive high performance liquid chromatography with fluorescence derivatization approach based on Sonogashira coupling reaction for determination of ethinyl estradiol in river water samples [J] . Ali Marwa F. B., Uejo Yurina, Kishikawa Naoya, Journal of chromatography, A: Including electrophoresis and other separation methods . 2020,第1期

机译：基于Sonogashira偶联反应的荧光衍生化方法选择性和高敏感的高效液相色谱法测定河水样品中乙炔雌二醇
3. Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes. [J] . Tron GC, Pirali T, Billington RA, Medicinal research reviews . 2008,第2期

机译：点击化学反应在药物化学中的应用：叠氮化物和炔烃之间的1,3-偶极环加成反应的应用。
4. APPLICATION OF A NOVEL PRE-CHARGED AND HIGHLY SPECIFIC FLUORINATED AZIDE FOR THE TRACE ANALYSIS OF ETHINYL ESTRADIOL USING A COPPERCATALYZED CLICK REACTION [C] . Priyanka Chitranshi, Lucie Loukotkova, Goncalo Gamboa da Costa ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：使用铜催化鼠标咔哒咔哒咔哒咔哒咔啉+乙炔雌二醇痕量分析的新型预充电和高度氟化叠氮化物
5. Poly(Triazole) Networks via Photo-Initiated Click Reactions: Copper-Catalyzed Azide-Alkyne Cycloaddition Polymerization and Thiol-Norbornene Polymerization [D] . Wang, Xiance. 2021

机译：聚（三唑）网络通过光起动的咔哒反应：铜催化的叠氮化物 - 炔烃环加成聚合和硫醇 - 降冰片烯聚合
6. CLICK-17 a DNA enzyme that harnesses ultra-low concentrations of either Cu+ or Cu2+ to catalyze the azide-alkyne ‘click’ reaction in water [O] . Kun Liu, Prince Kumar Lat, Hua-Zhong Yu, 2020

机译：CLICK-17一种DNA酶可利用超低浓度的Cu +或Cu2 +催化水中叠氮炔的点击反应
7. Original Fluorinated Copolymers Achieved by Both Azide/Alkyne “Click” Reaction and Hay Coupling from Tetrafluoroethylene Telomers [O] . Soules, Aurelien, Ameduri, Bruno, Boutevin, Bernard, 2010

机译：通过叠氮化物/炔烃的“点击”反应和四氟乙烯端粒的干草偶联获得的原始氟化共聚物

APPLICATION OF A NOVEL PRE-CHARGED AND HIGHLY SPECIFIC FLUORINATED AZIDE FOR THE TRACE ANALYSIS OF ETHINYL ESTRADIOL USING A COPPERCATALYZED CLICK REACTION

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