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首页> 外文会议>International Solid-State Sensors, Actuators and Microsystems Conference >ONE STEP INTEGRATION OF GOLD COATED SENSORS WITH OSTE POLYMER CARTRIDGES BY LOW TEMPERATURE DRY BONDING
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ONE STEP INTEGRATION OF GOLD COATED SENSORS WITH OSTE POLYMER CARTRIDGES BY LOW TEMPERATURE DRY BONDING

机译：黄热干粘接用骨涂层盒的金涂层传感器一步一体化

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摘要

We propose and demonstrate a novel one step method to integrate gold coated sensors with cartridges by dry covalent bonding. The cartridges are replica molded in an UV-curable off-stoichiometry thiol-ene (OSTE) polymer, featuring an excess of thiol functional groups that covalently bond to the surface of gold coated sensors upon contact. The method is demonstrated by the integration of a gold coated quartz crystal to a microfludic OSTE cartridge. The resulting bond interface is shown to be completely homogenous and void free and the package is tested successfully to a differential pressure of up to 2 bars. The performance of the biosensor chip is evaluated by measuring the unspecific binding of 0.5% albumin, resulting in a total frequency drop 205 Hz. This approach delivers a simple but rapid high quality integration aiming for the production of robust, low cost and disposable biosensor chips.
机译：我们提出并展示了一种新颖的一种步进方法，通过干燥的共价键合将金涂层传感器整合到盒中。盒在UV可固化的脱离化学计量硫醇 - 烯醇（OSTE）聚合物中模塑，其具有过量的硫醇官能团，其在接触时与金涂覆的传感器的表面共价键合。通过将金涂覆的石英晶体集成到微型玻璃骨盒中，证明了该方法。所得到的粘合界面被示出为完全均匀，并且不空闲，并且将包装成功地测试到最多2巴的差压。通过测量0.5％白蛋白的未特异性结合来评估生物传感器芯片的性能，得到总频率下降205Hz。这种方法提供了一种简单但快速的高质量集成，旨在生产坚固，低成本和一次性的生物传感器芯片。

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