Application of the Robotic Sample Preparation Program (RSPP) to Sample Dilutions for the Determination of BMS-562086 in Human Plasma by LC-MS/MS

机译：机器人样品制备程序（RSPP）在通过LC-MS / MS测定人血浆中BMS-562086的稀释液

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RSPP enables sample preparation and dilution to be fully automated. It is easy to use and flexible to meet the needs of multiple users. Preparation of two 96-well plates of samples including the sample dilution can be completed within 1.5 hours, which saved at least 50percent of the time compared with manual preparation. The results for the analysis of BMS-562086 in human plasma using RSPP demonstrate excellent ruggedness for diluted samples and that the process can be used in the regulated bioanalysis. This strategy will significantly reduce human errors during sample dilution, greatly improve data quality and increase bioanalytical productivity in drug development.

机译：RSPP使样品制备和稀释能够完全自动化。易于使用和灵活，以满足多个用户的需求。制备包括样品稀释的样品的两种96孔板可以在1.5小时内完成，与手动制备相比，至少节省了至少50平方。使用RSPP分析人类血浆中BMS-562086的结果表明了稀释样品的优异粗糙度，并且该方法可用于调节的生物分析。该策略将在样品稀释过程中显着降低人类误差，大大提高数据质量并提高药物开发中的生物分析生产力。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2010年||共1页
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Hao Jiang; Zheng Ouyang; Naiyu Zheng; Jianing Zeng; Mark E. Arnold;
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中图分类 TB994.5-53;
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Application of the Robotic Sample Preparation Program (RSPP) to Sample Dilutions for the Determination of BMS-562086 in Human Plasma by LC-MS/MS

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