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Gastric Stromal Tumors - Histopathological, Clinical and Therapeutical Aspects

机译：胃基质肿瘤 - 组织病理学，临床和治疗方面

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Background. The aim of this study is to present our experiences concerning a rare form of gastric tumor - gastric stromal tumor (gastric GIST).Methodology. We reviewed data of five patients with gastric GIST, who were admitted in our department before 2005.Results. There were three females and two males with a mean age of 70 (range 63-75). Gastric tumor was the preoperative diagnosis in all cases. During surgery we discovered gastric tumors of 4, 5, 10, 12 and 20 cm in largest diameter. We performed tumor resection with a security limit of 2 cm (four cases) and gastric resection (one case), without lymphadenectomy. One patient developed an anastomotic fistula with a good evolution under conservative treatment. No other major complication was recorded. Immunohistochemistry study diagnosed gastric GIST by identifying the CD117 marker (c-kit). Postoperatively, none of our patients received chemotherapy (Imatinib). Two patients died due to peritoneal and hepatic metastases at nine months respectively two years after operation (high grade tumors).
机译：背景。本研究的目的是展示我们关于含有稀有形式的胃肿瘤 - 胃部肿瘤（胃部）的经验。方法。我们在2005年之前审查了胃科患者的五名患者的数据。结果。有三个女性和两龄男性，平均年龄为70（范围63-75）。胃肿瘤是所有病例的术前诊断。在手术期间，我们发现了4,5,10,12和20cm的胃肿瘤最大直径。我们进行了肿瘤切除，安全限度为2厘米（四种情况）和胃切除（一种情况），没有淋巴结切除术。一名患者在保守治疗下开发出具有良好演变的吻合瘘。没有记录其他重症并发症。免疫组织化学通过鉴定CD117标记（C-Kit）来诊断胃癌。术后，我们的患者都没有接受化疗（伊马替尼）。两名患者因腹膜和肝脏转移而死亡，分别在九个月后术后两年（高等级肿瘤）。

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