Mathematical modeling of heart rate and blood pressure variations due to changes in breathing pattern

机译：心率和血压变化的数学建模引起的呼吸模式变化

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Analysis of the heart rate (HR) variation due to respiration, known as respiratory sinus arrhythmia (RSA), is a method to assess the autonomic nervous system (ANS) function. In this paper a physiologically-based mathematical model consisting of the cardiorespiratory system and ANS control has been used in order to study the cardiovascular response (mean arterial blood pressure and HR) to breathing with different respiration rates and tidal volumes. Simulation results show that RSA has its maximal amplitude at the respiration frequency of 0.12 Hz and that RSA amplitude varies linearly by tidal volume. These results are in agreement with real data from the literature. In addition, the amplitude of the variations of the simulated blood pressure (BP) in each respiratory cycle is maximum at almost the same respiratory rate as RSA.

机译：分析由于呼吸而导致的心率（HR）变异，称为呼吸道性心律失常（RSA），是评估自主神经系统（ANS）功能的方法。在本文中，使用了由心肺系统和ANS控制组成的基于生理学的数学模型，以研究心血管反应（平均动脉血压和HR），以不同的呼吸率和潮汐量呼吸。仿真结果表明，RSA在0.12Hz的呼吸频率下具有其最大幅度，并且RSA幅度通过潮气量线性变化。这些结果与文献中的真实数据一致。另外，每个呼吸循环中的模拟血压（BP）的变化的幅度最大化为与RSA几乎相同的呼吸速率。

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《Iranian Conference on Biomedical Engineering》|2013年||共5页
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Goldoozian Layli S.; Zahedi Edmond;
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中图分类生物医学工程;
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autonomic nervous system; cardiorespiratory system; respiratory sinus arrhythmia;

机译：自主神经系统;心肺系统;呼吸鼻窦心律失常;

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Mathematical modeling of heart rate and blood pressure variations due to changes in breathing pattern

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