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3-D electrical model of a neuroprosthesis stimulator based on the concept of stimulus router system

机译：基于刺激路由器系统概念的神经高原刺激器3-D电气模型

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摘要

Lost sensory or motor functions can be restored using electrical neural prostheses (NP), which include surface NPs, implanted or subcutaneous NPs and the more recent Stimulus Router System (SRS). The latter type of NP outperforms the other types in its selective excitation and least invasiveness. In each case, the achieved performance depends on a multitude of design factors among which the electrical excitation waveform shape, frequency, duration of pulses, configuration of electrodes, number of intervals, thermal conditions and electrode material. To investigate the effects of these parameters on the distribution of electric current inside biological tissues, numerical modeling can be employed as a powerful computational method. In this work, a 3-D electrical model is proposed to simulate the distribution of electric potentials and currents in the adult human forearm for an SRS NP. At the frequency of 50Hz and for a 5mA square waveform current source, results of our simulation show that the ratio of the current flowing inside the implanted conductor to the current applied to the cathodal electrode (capture ratio) is approximately equal to 2.02%. This value is close to the experimentally reported result for the SRS, 1.9%, giving an absolute error of 0.12% and relative error of 6.3%.
机译：失去感觉或运动功能都可以使用电神经假体（NP），其包括表面的NP，植入或皮下的NP和最近的激励路由器系统（SRS）被恢复。后一种类型的NP在其选择性的激励和至少侵袭优于其它类型的。在每种情况下，所实现的性能取决于设计因素众多其中电激励波形形状，频率，脉冲持续时间，电极的结构，间隔的热条件和电极材料的数量。为了研究对电流的内部生物组织的分布这些参数的影响，数值模拟可以用作一个强大的计算方法。在这项工作中，3-d的电模型，提出了模拟电势和电流的在成人前臂用于SRS NP的分布。为50Hz的和用于5毫安方波电流源的频率，我们的模拟的结果显示，所植入的导体到当前内部流动的电流的比率施加到阴极电极（捕获比）大约等于2.02％。这个值接近于针对SRS，1.9％，得到0.12％的绝对误差和相对误差的6.3％的实验报告结果。

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