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A new deconvolution method using antidiffusion for high resolution radioisotopic imaging

机译：一种新的消压法，用于高分辨率放射性同位成像的防肌

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Radioisotopic investigations are very useful for functional diagnosis. However, visual analysis of images is lowered by blurring due to impulse response size and by their granular aspect due to low statistics. Acquired images result in the convolution between original object and detector spatial impulse response. Classical deconvolution methods used for radioisotopic image restoration fail due to bad signal to noise ratio. A new deconvolution process including two steps is designed. The first stage reduces acquired images statistical noise by applying a 2nd order Butterworth low-pass filter. As the detector response shape may also be viewed as a 2D heat diffusion process, the deconvolution is done by running the diffusion equation into minus time. Tests were performed on physical phantom and on clinical thyroid scintigraphies acquired with IRIS (ARIES) high resolution gamma imaging probe. On physical phantom, cold spherical nodules as small as 4 mm in diameter are clearly enhanced on restored images, and diagnosis is improved.
机译：放射性同位素调查对于功能诊断非常有用。然而，由于脉冲响应尺寸和由于低统计而导致的脉冲，通过模糊地降低图像的视觉分析。获取的图像导致原始对象与检测器空间脉冲响应之间的卷积。用于放射性同位素图像恢复的经典解卷积方法由于信噪比不良而失效。设计了一种新的解构过程，包括两个步骤。第一阶段通过应用2ND阶Butterworth低通滤波器来减少获取的图像统计噪声。由于检测器响应形状也可以被视为2D热扩散过程，通过将扩散方程运行到减去时间来完成折折叠。用虹膜（白羊座）高分辨率伽马成像探针在物理幻像和临床甲状腺闪烁上进行测试。在物理幻影上，在恢复的图像上明确提高了小于直径为4mm的冷球形结节，并且改善了诊断。

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