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Investigating the effects of compressional and elastic photoacoustic waves to predict transcranial photoacoustic image quality for guidance of minimally invasive neurosurgeries

机译:调查压缩和弹性光声波的影响,以预测微创神经诊疗的指导的经颅光声图像质量

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Patient simulations can be a powerful tool to plan placement of photoacoustic imaging components for surgical guidance. We previously used compressional-wave-only simulations to identify optimal acoustic windows for transcranial photoacoustic imaging. Elastic simulations, which include both compressional and shear waves, are expected to more accurately represent the physical transcranial acoustic process. However, elastic simulations are timing-consuming and memory intensive. This paper contains a comparison of compressional and elastic wave simulations to determine which option is more suitable for preoperative surgical planning. Compressional and elastic photoacoustic k-Wave simulations were performed based on a CT volume of a human cadaver head. Photoacoustic sources were placed in the locations of the internal carotid arteries and likely positions of neuro-surgical instrument tips. Transducers received signals from three acoustic windows (i.e., the ocular, nasal, and temporal regions). Target visibility, image-based target size estimates, and target-to-instrument distances were measured using the generalized contrast-to-noise ratio, resolution, and relative source distances, respectively, for each simulation method. The generalized contrast-to-noise ratio and resolution measurements were equivalent between compressional and elastic simulations. Relative source distance measurements were within 0.1 mm of the true distances. These results indicate that it is sufficient to utilize the less time-consuming, less memory-intensive compressional wave simulations for presurgical planning.
机译:患者模拟可以是一个强大的工具,用于计划放置光声成像组件以进行手术指导。我们以前使用的压缩波仿真识别用于经颅光声成像的最佳声学窗口。包括压缩和剪切波的弹性模拟预期更准确地代表物理经颅声学过程。然而,弹性模拟是消耗时间和内存密集的。本文含有压缩和弹性波模拟的比较,以确定哪种选项更适合于术前手术规划。基于人尸体头的CT体积进行压缩和弹性光声k波模拟。光声源被置于内部颈动脉的位置,并且可能是神经外科仪器提示的位置。换能器接收来自三个声窗(即,眼部,鼻腔和颞区)的信号。针对每个模拟方法,使用广义对比度,分辨率和相对源距离测量目标可见性,基于图像的目标大小估计和目标到仪器距离。广义对比度和分辨率测量值等同于压缩和弹性模拟之间。相对源距离测量在真实距离的0.1毫米内。这些结果表明,利用较少的耗时,更少的内存密集型压缩波模拟足以进行预设规划。

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