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The Clinical Characteristics and Treatment of 78 Patients with Severe Acute Respiratory Syndrome

机译：78例重症急性呼吸综合征78例临床特征及治疗

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Objective To observe the clinical characteristics of severe acute respiratory syndrome (SARS) disease, explore and evaluate the effective treatment regimen. Methods Retrospective analysis of clinical presentation, laboratory investigation and treatment from 78 patients with SARS. Results The common symptoms of SARS patients were fever, dry cough and shortness of breath. White blood cell counts were normal or decreased in most of SARS cases on the first onset stage. CD4~+ and CD8~+ T lymphocytes in peripheral blood decreased during the progressive stage. Serum alanine aminotransferase and creatine kinase levels were elevated in 33.3% and 25.6% of the patients, respectively. In some cases, the respiratory symptoms and signs were not as severe as the conditions of the chest radiography. General combination therapy include antiviral, empirical antibiotics, corticosteroid and oxygen therapy was performed. Conclusions SARS is highly contagious with sever acute damage of the respiratory system, but it also implicates other organs, such as the liver and heart. The patients should be carefully observed and identified its progress stage in time by the different features. General combination therapy could improve the outcome.

机译：目的观察严重急性呼吸综合征（SARS）疾病的临床特征，探索和评估有效治疗方案。方法回顾性分析78例SARS的临床介绍，实验室调查和治疗。结果SARS患者的常见症状是发烧，干咳和呼吸急促。在第一个发病阶段的大部分SARS病例中，白细胞计数正常或降低。在进步阶段，外周血下的CD4〜+和CD8〜+ T淋巴细胞减少。血清丙氨酸氨基转移酶和肌酸激酶水平分别以33.3％和25.6％的患者升高。在某些情况下，呼吸系统症状和迹象并不像胸部射线照相的条件一样严重。一般组合疗法包括抗病毒，经验抗生素，皮质类固醇和氧疗法。结论SARS对呼吸系统的急性损害感染了高度传染性，但它也含有其他器官，例如肝脏和心脏。应仔细观察患者，并通过不同的特征在时间上识别其进展阶段。一般组合疗法可以改善结果。

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《International science symposium on SARS》|2003年||共5页
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作者
FAN Xiaoling; SUN Jingyuan; LIU Junmin; DING Jingqiu;
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中图分类传染病;
关键词
severe acute respiratory syndrome; clinical therapy;

机译：严重急性呼吸综合征;临床治疗;

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4. The Clinical Characteristics and Treatment of 78 Patients with Severe Acute Respiratory Syndrome [C] . FAN Xiaoling, SUN Jingyuan, LIU Junmin, Proceedings of International Science Symposium on SARS . 2003

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5. Severe Acute Respiratory Syndrome (SARS): From diagnosis to clinical management. [D] . Lee, Nelson, Lai Shun. 2007

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The Clinical Characteristics and Treatment of 78 Patients with Severe Acute Respiratory Syndrome

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