首页> 外文会议>International Conference on Functional Imaging and Modeling of the Heart >Left to Right Atrial Electrophysiological Differences: Substrate for a Dominant Reentrant Source during Atrial Fibrillation
【24h】

Left to Right Atrial Electrophysiological Differences: Substrate for a Dominant Reentrant Source during Atrial Fibrillation

机译:左转心房电生理学差异:心房颤动期间的主要旋流源的底物

获取原文

摘要

Experimentally observed differences in the action potential (AP) properties - primarily, refractoriness - between the left (LA) and right (RA) atria are believed to be important in maintaining atrial fibrillation. We incorporate AP models for single LA and RA cells into 2D atrial tissue models and study the role of tissue heterogeneity in global interaction between reentrant spiral waves in the LA and RA. Our simulations show that shorter refractoriness in the LA translates into a shorter period of spiral rotation, and as a result, reentry in the LA dominates the overall excitation patterns in the atria.
机译:实验观察到动作电位(AP)性质的差异 - 主要是耐火性 - 左(la)和右(Ra)Atria被认为在保持心房颤动方面是重要的。我们将单个LA和RA细胞的AP模型掺入2D心房组织模型,研究组织异质性在LA和RA中旋转螺旋波之间的全局相互作用中的作用。我们的模拟表明,LA中的较短耐火性转化为螺旋旋转的较短时期,因此,LA中的再入式主导阿里亚的整体励磁模式。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号