An Inverse Spectral Method to Localize Discordant Alternans Regions on the Heart from Body Surface Measurements

机译：一种逆频谱方法，以定位心脏表面测量心脏中的不间断的交替区域

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Spatially discordant T-wave alternans (TWA) has been shown to be linked to the genesis of ventricular fibrillation. Identification of discordant TWA through spatial characterization of TWA patterns in the heart has the potential to improve sudden cardiac death risk stratification. In this paper we present a method to solve a new variant of the inverse problem in electrocardiography that is tailored to estimate the TWA regions on the heart from non-invasive measurements on the body surface. We evaluate our method using both body surface potentials synthesized from heart surface potentials generated with ECGSIM and from potentials measured on a canine heart, and we show that this method detects the main regions in the heart undergoing TWA.

机译：已经显示出空间不安的T波替者（TWA）与心室颤动的成因相关联。通过心脏中TWA模式的空间表征不间断的鉴定，具有改善突发的心脏死亡风险分层。在本文中，我们介绍了一种方法来解决心电图中的逆问题的新变体，其定制，以估计心脏的无侵入性测量在心脏表面上的心脏上的细胞区域。我们使用由ECGSIM产生的心脏表面电位合成的身体表面电位和在犬心脏上测量的电位合成的体表电位来评估我们的方法，并且我们表明该方法检测到接受TWA的心脏中的主要区域。

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《International Conference on Functional Imaging and Modeling of the Heart》|2013年||共8页
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Jaume Coll-Font; Burak Erem; Alain Karma; Dana H. Brooks;
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中图分类 616.1/20754;
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Inverse Spectral; Method; to;

机译：逆光谱;方法;到;

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专利

1. Can body surface microvolt T-wave alternans distinguish concordant and discordant intracardiac alternans? [J] . FloréV., ClausP., SymonsR., PACE: Pacing and clinical electrophysiology . 2013,第8期

机译：体表微伏T波交替体能否区分一致和不一致的心内交替体？
2. Optimal wavelengths obtained from laws analogous to the Wien's law for monospectral and bispectral methods, and general methodology for multispectral temperature measurements taking into account global transfer function including non-uniform emissivity of surfaces [J] . Rodiet Christophe, Remy Benjamin, Degiovanni Alain Infrared physics and technology . 2016,第Null期

机译：从类似于单光谱和双光谱方法的维恩定律的定律获得的最佳波长，以及考虑到全局传递函数（包括表面的不均匀发射率）的多光谱温度测量的通用方法
3. Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients [J] . Ilija Uzelac, Yanyan C. Ji, Daniel Hornung, Frontiers in Physiology . 2017,第10期

机译：同时定量朗格多夫灌流兔心脏中电压和细胞内钙的空间不一致的交替子的定量以及与心脏动作电位和钙瞬变模型的不一致
4. An Inverse Spectral Method to Localize Discordant Alternans Regions on the Heart from Body Surface Measurements [C] . Jaume Coil-Font, Burak Erem, Alain Karma, International conference on functional imaging and modeling of the heart . 2013

机译：通过体表测量来定位心脏上不一致的交替区域的逆谱方法
5. Localization of subsurface fluorescent lesions using surface spectral measurements. [D] . Kolste, Kolbein. 2016

机译：使用表面光谱测量来定位地下荧光病变。
6. A Potential-Based Inverse Spectral Method to Non-Invasively Localize Discordant Distributions of Alternans on the Heart from the ECG [O] . Jaume Coll-Font, Burak Erem, Dana H. Brooks -1

机译：基于电势的反谱方法通过心电图非侵入性地定位心脏上交替蛋白的不一致分布
7. Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients [O] . Ilija Uzelac, Yanyan C. Ji, Daniel Hornung, 2017

机译：Langendorff灌注兔心脏电压和细胞内钙中空间不一致交替的同时定量和心脏动作电位和钙瞬变模型的不一致性

An Inverse Spectral Method to Localize Discordant Alternans Regions on the Heart from Body Surface Measurements

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