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Spectral studies of polycyclic aromatic hydrocarbon interaction with human blood plasma

机译：人血浆多环芳烃相互作用的光谱研究

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Analysis of fluorescence spectra of polycyclic aromatic hydrocarbons in human blood plasma and human serum albumin solution allowed one to conclude that pyrene and also anthracene are predominantly distributed in the hydrophobic micro-phase of blood plasma proteins. In the solution of human blood plasma containing pyrene the nonmonotonic dependence of both the intensity of pyrene fluorescence and the index of polarity on the concentration of sodium dodecylsulfate added was observed. This should be connected with the reconstruction of the structure of protein globule under the surfactant action and cannot be explained only by the solubilization of pyrene in sodium dodecylsulfate micelles.

机译：人血浆中多环芳烃荧光谱分析，人血浆和人血清白蛋白溶液中的荧光光谱允许一个人得出结论，芘和蒽主要分布在血浆蛋白的疏水微阶段。在含有芘的人血浆溶液中，观察到芘荧光强度的非单调依赖性以及对添加的十二烷基硫酸钠浓度的极性指数。这应该与表面活性剂作用下的蛋白质球状结构的重建连接，并且才通过芘在十二烷基硫酸钠胶束中的溶解来解释。

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《Saratov Meeting》|2006年||共5页
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作者
A. G. Melnikov; A. B. Pravdin; V. I. Kochubey; G. V. Melnikov;
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原文格式 PDF
正文语种
中图分类光、激光生物医学;
关键词
huam plasma blood; protein; human serum albumin; polycyclic aromatic hydrocarbons; pyrene; anthracene; fluorescence; sodium dodecylsuphate;

机译：人血浆;蛋白质;人血清白蛋白;多环芳烃;芘;蒽;荧光;十二烷基硫酸钠;

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Spectral studies of polycyclic aromatic hydrocarbon interaction with human blood plasma

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