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首页> 外文会议>Conference on Photonic Therapeutics and Diagnostics >Optical Stimulation of the Cavernous Nerves in the Rat Prostate
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Optical Stimulation of the Cavernous Nerves in the Rat Prostate

机译：在大鼠前列腺中的阴囊神经的光学刺激

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Laser nerve stimulation has recently been studied as an alternative to electrical stimulation in neuroscience. Advantages include non-contact stimulation, improved spatial selectivity, and elimination of electrical stimulation artifacts. This study explores laser stimulation of the rat cavernous nerves, as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy. The cavernous nerves were surgically exposed in a total of 10 male rats. A Thulium fiber laser stimulated the nerves, with a wavelength of 1870 nm, pulse energy of 7.5 mJ, radiant exposure of 1 J/cm~2, pulse duration of 2.5 ms, pulse rate of 10 Hz, and 1-mm laser spot diameter, for a stimulation time of 60 s. A significant increase in the intracavernosal pressure was detected upon laser stimulation, with pressure returning to baseline levels after stimulation. This study demonstrates the feasibility of non-contact laser stimulation of the cavernous nerves using near-infrared laser radiation.
机译：最近研究了激光神经刺激作为神经科学中的电气刺激的替代方案。优点包括非接触刺激，改善空间选择性和消除电刺激伪影。本研究探讨了大鼠海绵体神经的激光刺激，作为神经备受自由基前列腺切除术期间电神经映射的潜在替代品。海绵状神经在全外暴露于10只雄性大鼠。纤维激光刺激神经，波长为1870nm，脉冲能为7.5 mj，辐射暴露为1 j / cm〜2，脉冲持续时间为2.5ms，脉冲速率为10 hz，脉冲速率为10 hz和1mm激光光斑直径，对于60秒的刺激时间。激光刺激后检测到腔内压力的显着增加，刺激后的压力返回基线水平。本研究证明了使用近红外激光辐射的不接触激光刺激的不接触激光刺激的可行性。

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