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首页> 外文会议>World Congress for Microcirculation >Visualization of Microvessels Deeply Embedded in Cerebral Cortex of Rats by Doppler Optical Coherence Tomography
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Visualization of Microvessels Deeply Embedded in Cerebral Cortex of Rats by Doppler Optical Coherence Tomography

机译：通过多普勒光学相干断层扫描，深入嵌入大鼠大鼠脑皮层的微血管的可视化

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Microvessels deeper than 1 mm within the cortical tissue of rat brain were successfully visualized 3-dimensionally by the Doppler OCT (optical coherence tomography) technique. Penetrating arterioles and venules can be discriminated based on the direction and pulsatility of blood flow. The information of structure and blood flow of microvessels in the direction of depth can help us to understand blood flow regulation among layers as well as functional columns of cerebral cortex.Cerebral cortex is a few mm thick and it has both layered and columnar structures with submillimeter scale. To elucidate the so called "neuro-vascular coupling" phenomena down to such small scale structures, it is necessary to know microvascular structure and function 3-dimensionally with sufficient spatial resolutions. However, microvessels deeper than about 100 mum are difficult to observe by light microscopy. MRI and ultrasonography are deficient in spatial resolution.
机译：通过多普勒OCT（光学相干断层扫描）技术在大鼠脑皮质组织内更深于1mm的微血管。 可以基于血流的方向和脉动性来区分渗透动脉杆菌和静脉。 微孔的结构和血流的信息在深度方向上可以帮助我们理解层间的血液流量调节以及脑皮质的功能柱。Cortex的功能柱是几毫米厚，并且它具有淹没倍数的分层和柱状结构。 规模。 为了将所谓的“神经血管偶联”现象阐明下降到这种小规模结构，需要利用足够的空间分辨率来了解微血管结构和三维功能。 然而，光学显微镜难以观察到大于约100毫米的微血管。 MRI和超声检查缺乏空间分辨率。

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