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Mouse whole-body organ mapping by non-rigid registration approach

机译:通过非刚性登记方法鼠标全身器官映射

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Automatic small animal whole-body organ registration is challenging because of subject's joint structure, posture and position difference and loss of reference features. In this paper, an improved 3D shape context based non-rigid registration method is applied for mouse whole-body skeleton registration and lung registration. A geodesic path based non-rigid registration method is proposed for mouse torso skin registration. Based on the above registration methods, a novel non-rigid registration framework is proposed for mouse whole-body organ mapping from an atlas to new scanned CT data. A preliminary experiment was performed to test the method on lung and skin registration. A whole-body organ mapping was performed on three target data and the selected organs were compared with the manual outlining results. The robust of the method has been demonstrated.
机译:由于受试者的关节结构,姿势和位置差和参考功能损失,自动小动物全身器官注册是具有挑战性的。本文施加了一种改进的3D形状上下文的非刚性登记方法,用于小鼠全身骨架登记和肺登记。提出了一种基于测地的非刚性登记方法,用于小鼠躯干皮肤注册。基于上述注册方法,提出了一种从地图集到新的扫描CT数据的小鼠全身器官映射的新颖的非刚性登记框架。进行初步实验以测试肺和皮肤注册的方法。在三个目标数据上进行全身器官映射,并将所选器官与手动概述结果进行比较。已经证明了该方法的稳健。

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