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Relationship between serum adiponectin with anthropometrical and lipid profile biochemical indexes in obese adult men

机译:肥胖成年男性血清脂联素与人类血清血清生化指标的关系

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Background and objective: This study was conducting aimed at comparing adiponectin serum levels in obese male adults with their peer normal weight subjects as well as determining the relationship between anthropometrical and lipid profile indices and serum adiponectin in obese men. Material and methods: Body mass index and other anthropometrical variables as well as concentrations of glucose, triglyceride, total cholesterol and low and high density lipoprotein were measured in 45 obese male adults after 12 to 14 hours overnight fasting and their correlation with serum adiponectin levels were determined. Also, fasting serum adiponectin levels were measured in 35 male adults with normal weight. T statistical method was used to compare adiponectin levels of obese group with normal weight group and regression analysis was used in SPSS software version 15 environment to determine the relationship of adiponectin with each anthropometrical and biochemical variables in obese subjects (P ≤ 0.05). Results: adiponectin Serum level in obese subjects were significantly lower than those with normal weight (P = 0.021). Adiponectin level had a significant correlation with total cholesterol, low density lipoprotein, glucose, and systolic and diastolic blood pressure and age of subjects (P ≤ 0.05). Conclusion: The significant relationship between adiponectin and some cardiovascular risk factors in this study supports the hypothesis that reduction of systemic levels of this hormone is associated with some cardiovascular risk factors.
机译:背景和目的:本研究开展旨在与他们同行体重正常的受试者相比,肥胖男性成年人血清脂联素水平以及确定人体测量学和血脂指标和肥胖男性血清脂联素之间的关系。材料和方法:身体质量指数和其它人体测量学的变量以及葡萄糖,甘油三酯,总胆固醇和低密度和高密度脂蛋白的浓度在45只肥胖雄性成虫测量后12至14小时过夜禁食和它们与血清脂联素水平的相关性是决定。另外,在35名男性成人正常体重测量空腹血清脂连蛋白水平。使用Ť统计方法肥胖组的脂连蛋白水平与在SPSS软件版本15环境中使用体重正常组和回归分析,以确定脂联素与肥胖受试者每个人体测量学和生物化学变量(P≤0.05)的关系进行比较。结果:脂连蛋白的血清水平在肥胖受试者比正常体重(P = 0.021)的显著降低。脂连蛋白水平与总胆固醇,低密度脂蛋白,葡萄糖和收缩和舒张血压和受试者年龄(P≤0.05)一个显著相关性。结论:脂联素,在这项研究中的一些心血管危险因素之间的关系显著支持减少这种激素的全身水平与某些心血管危险因素相关的假说。

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