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Multiparametric Microsensors on Lab-on-chip Systems for the Detection of Dissolved Substances

机译:用于检测溶解物质的片上系统上的多体微传感器

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A microsensor chip fabricated in silicon technology was developed at the Heinz Nixdorf-Lehrstuhl fur Medizinische Elekronik at Technische Universitat Munchen. This BioChip contains microsensors for measurement of pH, dissolved oxygen, bioimpedance and temperature. Furthermore it was possible to realize a new sensor for dissolved redox active substances. Using a noble metal electrode (NME) surrounding an ISFET (ion sensitive field effect transistor) pH-sensor it was possible to measure dissolved oxygen concentration indirectly via the resulting change in the pH value when applying -700mV at the NME. The concept of this O_2-FET was extended successfully also for measuring other dissolved redox-active substances, using a cyclovoltammetric (CV) scanning mode. With this approach of a so called CV-FET sensor, dissolved substances can be detected according to their specific CV patterns.
机译:在Heinz Nixdorf-Lehrstuhl毛皮Medizinische Elekronik在Technische Univeritat Munchen开发了一种在硅技术中制造的微传感器芯片。 该生物芯片含有用于测量pH,溶解氧,生物阻抗和温度的微传感器。 此外,可以实现用于溶解的氧化还原活性物质的新传感器。 使用围绕ISFET(离子敏感场效应晶体管)pH传感器的贵金属电极(NME),可以在施加-700mV时通过所得到的pH值变化间接测量溶解的氧浓度。 使用Cyclovoletric(CV)扫描模式,成功地成功地延长了该O_2-FET的概念,用于测量其他溶解的氧化还原活性物质。 利用所谓的CV-FET传感器的这种方法,可以根据其特定的CV图案检测溶解物质。

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