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首页> 外文会议>World Congress of the World Society for Pediatric Infectious Diseases >The role of PLEX-ID in diagnosing multiple etiology systemic bacterial infections - case presentation
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The role of PLEX-ID in diagnosing multiple etiology systemic bacterial infections - case presentation

机译：plex-id在诊断多病因系统细菌感染方面的作用 - 案例介绍

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Summary: Systemic bacterial infections are an important cause of mortality and morbidity in children. Most of the times, there is only one causing agent, but, in rare cases, the etiology is polymicrobial. In this situation, establishing the diagnosis is difficult and most of the times it cannot be done through usual means. In this article, we present the case of a 6 years old male patient admitted in the Intensive Care Unit of The National Institute of Infectious Diseases "Prof. Dr. Matei Bals" with the diagnosis of acute meningoencephalitis. We have monitored the correlation of the etiological diagnosis obtained through classic laboratory methods with the diagnosis established through modern molecular methods, as well as the clinical and paraclinical evolution of the patient under treatment. With the aid of the molecular methods of diagnosis, we have identified two microorganisms: Mycobacterium tuberculosis and Acinetobacter baumannii. Subsequently, the polymicrobial etiology was confirmed through blood cultures. Although coinfection with two microorganisms is rare in an immunocompetent patient, the diagnosis was possible with the help of extremely fast molecular methods, which have allowed the identification of both agents and led to an adequate early treatment.
机译：发明内容：全身细菌感染是儿童死亡率和发病率的重要原因。大多数时候，只有一种致原因，但在极少数情况下，病因是多元化的。在这种情况下，建立诊断是困难的，大多数时间不能通过通常的手段来完成。在本文中，我们展示了6岁男性患者在国家传染病的重症监护疾病单位承认，诊断为急性脑膜炎的诊断。我们监测了通过经典实验室方法获得的病因诊断的相关性，通过现代分子方法建立的诊断，以及治疗患者的临床和梯形演化。借助于诊断的分子方法，我们已经确定了两种微生物：结核分枝杆菌和肺杆菌。随后，通过血液培养证实了多种状体病因。虽然在免疫活性患者中具有两种微生物的稀有罕见，但借助于极快的分子方法，诊断是可能的，这使得允许鉴定两种药剂并导致足够的早期治疗。

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