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CLINICAL APPLICATION OF THROMBOELASTOGRAPHY IN DOGS AND CATS

机译:血栓球运动在狗和猫的临床应用

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Assessment of hemostasis using thromboelastography (TEG) has received much attention recently, with adoption as a diagnostic tool in many referral and institutional centers. This seminar will review the application of this test for canine and feline patients, and present a review of the current literature on the topic.Numerous variables can be derived from the TEG tracing (Figure 1), but only a few are commonly used routinely. There are four standard variables that relate to clot formation. The reaction time or R time, measures the time in minutes from initiation of the test to first formation of fibrin and amplitude of 2mm. This is the usual endpoint of traditional plasma based tests, and becomes prolonged when there is a decrease in clotting factor activity. The K time measures the time in minutes from amplitude of2mm to 20mm, and is a representation of speed of clot formation. Alpha (commonly a or angle") is a measure in degrees of the angle tangential to the developing curve as K is reached. Finally, the maximum amplitude, or MA, is a measure in millimeters ofthe maximal amplitude reached and is an assessment of maximal clot strength, and overall stability of the clot. Additionally, G can be used as an assessment of clot strength, and is a derivative of MA in dynes/cm . Clot lysis variables LY30 and LY60 canbe determined if the tracing is allowed to run long enough, and are percent lysis at 30 and 60 minutes respectively, after determination of MA.
机译:使用血栓球运动(TEG)评估止血(TEG)最近受到了很多关注,通过作为许多转诊和制度中心的诊断工具。本次研讨会将审查此测试对犬类和猫科动物患者的应用,并对目前的文献进行了审查。可以从TEG跟踪中衍生出来的变量(图1),但只有少数几个常规使用。有四个标准变量与CLOT形成有关。反应时间或r时间,测量从测试开始的时间以首先形成纤维蛋白和2mm的振幅。这是传统等离子体基基测试的通常终点,并且当凝血因子活性降低时,延长。 K时间测量从2mm的幅度到20mm的分钟内的时间,并且是凝块形成速度的表示。 α(通常为A或角度“)是达到k的显影曲线的角度度的度量。最后,最大幅度或mA是达到最大幅度的毫米的衡量标准,并且是对最大的数量凝块的强度,以及凝块的整体稳定性。另外,G可以用作凝块强度的评估,是MA在染料中的衍生物/厘米。凝块裂解变量Ly30和Ly60 Canbe确定是否允许追踪速度足够,在测定mA之后,分别在30和60分钟的裂解百分比。

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