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PARANEOPLASTIC SYNDROMES IN LARGE ANIMAL PATIENTS

机译:大型动物患者的平原综合征

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Paraneoplastic syndromes are abnormalities/clinical signs that are caused by the presence of malignancies. A simple classification system that can be used to explain the etiology of these abnormalities is as follows:1) Signs due to substances produced by the cancer and released into systemic circulation. Examples include hormones, proteins, cytokines, electrolytes, metabolites, etc.2) Signs due to the consumption/loss of nutrients by the tumor. Examples include hypoglycemia, hypoalbuminemia, etc.3) Signs due to the body's response to the tumor. Examples include immune-mediated diseases, leukocytosis, erythrocytosis, anemia, cachexia, coagulopathies, etcWhile the true incidence of these syndromes is unknown in veterinary patients they are likely quite common in tumor bearing patients. A clear understanding of the pathogenesis of these syndromes is valuable in devising effective treatment plans. Further, their presence can be used as early indicators of disease or disease recurrence.
机译:Paraneoplastic综合征是由于恶性肿瘤的存在而导致的异常/临床迹象。 一种简单的分类系统,可用于解释这些异常的病因如下:1)由于癌症产生的物质和释放到系统性循环而导致的迹象。 实例包括由于肿瘤消耗/丧失营养物的消耗/丧失而导致的激素,蛋白质,细胞因子,电解质,代谢物等)标志。 实例包括由于身体对肿瘤的响应,低血糖,低聚蛋白血症等.3)标志。 实例包括免疫介导的疾病,白细胞增多症,红细胞增多,贫血,恶病症,凝血病等兽医患者的真正发病率在兽医患者中未知,它们在肿瘤患者中可能很常见。 清楚地了解这些综合征的发病机制在设计有效的治疗计划方面是有价值的。 此外,它们的存在可以用作疾病或疾病复发的早期指标。

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