• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Conference on Optical Coherence tomography and coherence domain optical methods in biomedicine XXI >Rat brain imaging using full field optical coherence microscopy with short multimode fiber probe
【24h】

Rat brain imaging using full field optical coherence microscopy with short multimode fiber probe

机译：大鼠脑成像采用全场光学相干显微镜显微镜，具有短万光纤探针

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We demonstrated FF OCM(full field optical coherence microscopy) using an ultrathin forward-imaging SMMF (short multimode fiber) probe of 50 μm core diameter, 125 μm diameter, and 7.4 mm length, which is a typical graded-index multimode fiber for optical communications. The axial resolution was measured to be 2.20 μm, which is close to the calculated axial resolution of 2.06 μm. The lateral resolution was evaluated to be 4.38 μm using a test pattern. Assuming that the FWHM of the contrast is the DOF (depth of focus), the DOF of the signal is obtained at 36 urn and that of the OCM is 66 um. The contrast of the OCT images was 6.1 times higher than that of the signal images due to the coherence gate. After an euthanasia the rat brain was resected and cut at 2.6mm tail from Bregma. Contacting SMMF to the primary somatosensory cortex and the agranular insular cortex of ex vivo brain, OCM images of the brain were measured 100 times with 2μm step. 3D OCM images of the brain were measured, and internal structure information was obtained. The feasibility of an SMMF as an ultrathin forward-imaging probe in full-field OCM has been demonstrated.
机译：我们使用超前向前成像SMMF（短多模光纤）探针为50μm芯直径，125μm，直径为7.4mm长度，展示FF OCM（全场光学相干显微镜），这是一个用于光学的典型分级索引多模光纤通讯。测量轴向分辨率为2.20μm，靠近计算出的2.06μm的轴向分辨率。使用测试模式评价横向分辨率为4.38μm。假设对比度的FWHM是DOF（焦深），信号的DOF在36瓮处获得，并且OCM的DOF是66μm。由于相干栅极，OCT图像的对比度比信号图像的对比度高6.1倍。在安乐死后，大鼠脑从BEGEGMA切割并切割2.6mm尾部。与SMMF接触到初级躯体感觉皮质和exvivo大脑的悬肿大的脑膜脑外皮层，OCM图像的大脑图像用2μm的步骤测量100次。测量大脑的3D OCM图像，并获得内部结构信息。已经证明了SMMF作为全场OCM中超前成像探针的可行性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号