• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Conference on Optical Coherence tomography and coherence domain optical methods in biomedicine XXI >Image-guided feedback for ophthalmic microsurgery using multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography
【24h】

Image-guided feedback for ophthalmic microsurgery using multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

机译：使用多模式术中扫描源光谱编码扫描激光眼镜和光学相干断层扫描的图像引导反馈

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Surgical interventions for ocular diseases involve manipulations of semi-transparent structures in the eye, but limited visualization of these tissue layers remains a critical barrier to developing novel surgical techniques and improving clinical outcomes. We addressed limitations in image-guided ophthalmic microsurgery by using microscope-integrated multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (iSS-SESLO-OCT). We previously demonstrated in vivo human ophthalmic imaging using SS-SESLO-OCT, which enabled simultaneous acquisition of en face SESLO images with every OCT cross-section. Here, we integrated our new 400 kHz iSS-SESLO-OCT, which used a buffered Axsun 1060 nm swept-source, with a surgical microscope and Truevision stereoscopic viewing system to provide image-based feedback. In vivo human imaging performance was demonstrated on a healthy volunteer, and simulated surgical maneuvers were performed in ex vivo porcine eyes. Densely-sampled static volumes and volumes subsampled at 10 volumes-per-second were used to visualize tissue deformations and surgical dynamics during corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. En face SESLO images enabled orientation and co-registration with the widefield surgical microscope view while OCT imaging enabled depth-resolved visualization of surgical instrument positions relative to anatomic structures-of-interest. Truevision heads-up display allowed for side-by-side viewing of the surgical field with SESLO and OCT previews for real-time feedback, and we demonstrated novel integrated segmentation overlays for augmented-reality surgical guidance. Integration of these complementary imaging modalities may benefit surgical outcomes by enabling real-time intraoperative visualization of surgical plans, instrument positions, tissue deformations, and image-based surrogate biomarkers correlated with completion of surgical goals.
机译：对眼部疾病的外科手术干预涉及眼睛中半透明结构的操纵，但这些组织层的可视化仍然是发展新外科技术和改善临床结果的关键障碍。我们通过使用显微镜 - 集成的多峰内术中扫描源探测扫描激光眼科和光学相干断层扫描（ISS-SESLO-OCT）来解决图像引导眼科显微镜的局限性。我们之前使用SS-Seslo-OCT在体内人体眼科成像中展示，这使得每章横截面都能够同时采集EN面部SESLO图像。在这里，我们集成了我们的新的400 kHz ISS-Seslo-OTT，它使用了缓冲的AXSUN 1060 NM扫描源，具有外科显微镜和TrueVision立体观看系统，以提供基于图像的反馈。体内人体影像学表现在健康的志愿者上证明，并且模拟的手术机动在离体猪眼中进行。在每秒10体积的致密采样的静态卷和体积用于在角膜扫描，压缩和解剖中可视化组织变形和外科动力学，以及视网膜扫描，压缩和升高。 EN面对SESLO图像使能方向和共同登记与宽场外科显微镜视图，而OCT成像使能够相对于兴趣解剖结构的外科仪器位置的深度分辨可视化。 TrueVision抬头显示允许使用SESLO和OCT预览的外科手术场的并排查看进行实时反馈，我们展示了用于增强现实手术指导的新型集成分割叠加。这些互补成像模型的整合可以通过能够通过能够进行外科计划，仪器位置，组织变形和基于图像的替代生物标志物的实时术中可视化来利用外科检查，与外科目标相关联。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号