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Preliminary Cancer Cell Line Results for the Polyester amines Derived From Reaction of Norfloxacin with Triphenylarsenic, Triphenylantimony, and Triphenylbismuth Dihalides

机译:衍生自诺氟沙星与三苯基甲烷,三苯基酰亚胺和三苯基铋二卤化物反应的聚酯胺的初步癌细胞系结果

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We have been engaged in the synthesis of a variety of metal-containing polymers for a variety of purposes. Most recently one focus is the synthesis and characterization of organotin-containing polymers as anticancer, antiviral, and antibacterial agents. 1-25 Some of this activity has involved employing biologically active agents as the Lewis base with the idea that this biological activity might impart particular biological characteristics to the polymer that would enhance the their ability to inhibit unwanted growth in cancers,1-18,21,22 viruses,10,19,20 and bacteria.3,7,20 It is recognized that a number of cancers appear to have connections with bacteria and so we recently synthesized a number of organotin-containing polymers from various antibiotics including penicillin related drugs such as ciprofloxacin,1,12-14 norfloxacin, 6,9 ampicillin, 9,23 and ticarcillin17.
机译:我们已经从事各种含金属聚合物的合成,用于各种目的。 最近的重点是合成和表征含有有机锡的聚合物作为抗癌,抗病毒和抗菌剂。 1-25其中一些活性涉及使用生物活性剂作为刘易斯的介绍,即这种生物活性可能向聚合物赋予聚合物的特定生物学特性,这将增强其抑制癌症的不需要生长的能力,1-18,21 ,22例病毒,10,19,20和细菌.3,7,20认识到,许多癌症似乎与细菌有关,因此我们最近从包括青霉素相关药物(包括青霉素相关药物)的各种抗生素合成了许多有机锡聚合物 如环丙沙星,1,12-14诺氟沙星,6,9 ampicillin,9,23和Ticarcillin17。

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